Structural basis of Hox specificity

被引：24
|
作者：
Wilson, DS [1 ]
Desplan, C
机构：
[1] Massachusetts Gen Hosp, Boston, MA 02114 USA
[2] Rockefeller Univ, New York, NY 10021 USA
来源：
NATURE STRUCTURAL BIOLOGY | 1999年 / 6卷 / 04期
关键词：
D O I：
10.1038/7524
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
On their own, the homeotic selector (Hox) transcriptional regulators bind very short, rather similar DNA sequences. To elevate their functional specificity, Hox proteins heterodimerize with other homeodomain-containing proteins. The structural basis for this fruitful partnership is now coming into view.
引用
收藏
页码：297 / 300
页数：4
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