In vivo evaluation of a novel, wrist-mounted arterial pressure sensing device versus the traditional hand-held tonometer
被引:12
作者:
Vardoulis, Orestis
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Microsoft Res, Redmond, WA 98052 USA
Ecole Polytech Fed Lausanne, Lab Hemodynam & Cardiovasc Technol, Lausanne, SwitzerlandMicrosoft Res, Redmond, WA 98052 USA
Vardoulis, Orestis
[1
,2
]
Saponas, T. Scott
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Microsoft Res, Redmond, WA 98052 USAMicrosoft Res, Redmond, WA 98052 USA
Saponas, T. Scott
[1
]
Morris, Dan
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Microsoft Res, Redmond, WA 98052 USAMicrosoft Res, Redmond, WA 98052 USA
Morris, Dan
[1
]
Villar, Nicolas
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Microsoft Res, Redmond, WA 98052 USAMicrosoft Res, Redmond, WA 98052 USA
Villar, Nicolas
[1
]
Smith, Greg
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Microsoft Res, Redmond, WA 98052 USAMicrosoft Res, Redmond, WA 98052 USA
Smith, Greg
[1
]
Patel, Shwetak
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Microsoft Res, Redmond, WA 98052 USA
Univ Washington, Seattle, WA 98195 USAMicrosoft Res, Redmond, WA 98052 USA
Patel, Shwetak
[1
,3
]
Tan, Desney
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Microsoft Res, Redmond, WA 98052 USAMicrosoft Res, Redmond, WA 98052 USA
Although hemodynamic parameters can be assessed non-invasively, state-of-the-art non-invasive systems generally require an expert operator and are not applicable for ambulatory measurements. These limitations have restricted our understanding of the continuous behavior of hemodynamic parameters. In this manuscript, we introduce a novel wrist-mounted device that incorporates an array of pressure sensors which can be used to extract arterial waveforms and relevant pulse wave analysis biomarkers. In vivo evaluation is performed with Bland-Altman analysis to compare the novel sensor to a gold-standard hand-held tonometer by assessing their reproducibility and agreement in peripheral augmentation index (AIx) estimation at the radial artery. Arterial waves from 28 randomly selected participants were recorded in a controlled environment. Initially we assess the reproducibility of AIx results for both devices. The intra-class correlation coefficient (ICC) and mean difference +/- SD were [0.913, 0.033 +/- 0.048] and [0.859, 0.039 +/- 0.076] for the hand-held and the wrist-mounted tonometer respectively. We then show that the AIx values derived from the novel tonometer have good agreement, accuracy, and precision when compared against the AIx values derived from the reference hand-held tonometer (ICC 0.927, mean difference 0.026 +/- 0.049). In conclusion, we have presented evidence that the new wrist-mounted arterial pressure sensor records arterial waveforms that can be processed to yield AIx values that are in good agreement with its traditional hand-held counterpart. (C) 2016 IPEM. Published by Elsevier Ltd. All rights reserved.
机构:
Columbia Univ, Dept Pharmacol, New York, NY 10032 USA
Columbia Univ, Dept Biomed Engn, New York, NY 10032 USAColumbia Univ, Dept Pharmacol, New York, NY 10032 USA
Ciaccio, Edward J.
Drzewiecki, Gary M.
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机构:
Rutgers State Univ, Dept Biomed Engn, New Brunswick, NJ 08901 USAColumbia Univ, Dept Pharmacol, New York, NY 10032 USA
机构:
Shandong Univ, Sch Control Sci & Engn, Sch Med, Inst Biomed Engn, Shandong, Peoples R China
MIT, Cambridge, MA 02139 USAShandong Univ, Sch Control Sci & Engn, Sch Med, Inst Biomed Engn, Shandong, Peoples R China
Li, Q.
Mark, R. G.
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机构:
MIT, Cambridge, MA 02139 USA
Harvard Univ, MIT, Div Hlth Sci & Technol, Cambridge, MA 02139 USAShandong Univ, Sch Control Sci & Engn, Sch Med, Inst Biomed Engn, Shandong, Peoples R China
机构:
Columbia Univ, Dept Pharmacol, New York, NY 10032 USA
Columbia Univ, Dept Biomed Engn, New York, NY 10032 USAColumbia Univ, Dept Pharmacol, New York, NY 10032 USA
Ciaccio, Edward J.
Drzewiecki, Gary M.
论文数: 0引用数: 0
h-index: 0
机构:
Rutgers State Univ, Dept Biomed Engn, New Brunswick, NJ 08901 USAColumbia Univ, Dept Pharmacol, New York, NY 10032 USA
机构:
Shandong Univ, Sch Control Sci & Engn, Sch Med, Inst Biomed Engn, Shandong, Peoples R China
MIT, Cambridge, MA 02139 USAShandong Univ, Sch Control Sci & Engn, Sch Med, Inst Biomed Engn, Shandong, Peoples R China
Li, Q.
Mark, R. G.
论文数: 0引用数: 0
h-index: 0
机构:
MIT, Cambridge, MA 02139 USA
Harvard Univ, MIT, Div Hlth Sci & Technol, Cambridge, MA 02139 USAShandong Univ, Sch Control Sci & Engn, Sch Med, Inst Biomed Engn, Shandong, Peoples R China