Binding MOAD, a high-quality protein-ligand database

被引：133

作者：

Benson, Mark L. ^{[1
]}

Smith, Richard D. ^{[2
]}

Khazanov, Nickolay A. ^{[1
]}

Dimcheff, Brandon ^{[3
]}

Beaver, John ^{[3
]}

Dresslar, Peter ^{[3
,4
]}

Nerothin, Jason ^{[4
]}

Carlson, Heather A. ^{[1
,2
,4
]}

机构：

[1] Univ Michigan, Bioinformat Grad Program, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Div Biophys Res, Ann Arbor, MI 48109 USA

[3] Torrey Path LLC, Ann Arbor, MI 48104 USA

[4] Univ Michigan, Dept Med Chem, Ann Arbor, MI 48109 USA

来源：

NUCLEIC ACIDS RESEARCH | 2008年 / 36卷

关键词：

D O I：

10.1093/nar/gkm911

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Binding MOAD (Mother of All Databases) is a database of 9836 proteinligand crystal structures. All biologically relevant ligands are annotated, and experimental binding-affinity data is reported when available. Binding MOAD has almost doubled in size since it was originally introduced in 2004, demonstrating steady growth with each annual update. Several technologies, such as natural language processing, help drive this constant expansion. Along with increasing data, Binding MOAD has improved usability. The website now showcases a faster, more featured viewer to examine the proteinligand structures. Ligands have additional chemical data, allowing for cheminformatics mining. Lastly, logins are no longer necessary, and Binding MOAD is freely available to all at http://www.BindingMOAD.org.

引用

页码：D674 / D678

页数：5

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