Apoptosis: eating sensibly

被引：18

作者：

Gregory, CD ^{[1
]}

Brown, SB ^{[1
]}

机构：

[1] Univ Edinburgh, MRC, Ctr Inflammat Res, Queens Med Res Inst, Edinburgh EH16 4TJ, Midlothian, Scotland

来源：

NATURE CELL BIOLOGY | 2005年 / 7卷 / 12期

关键词：

D O I：

10.1038/ncb1205-1161

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Phagocytes may engulf both apoptotic and viable cells via calreticulin on the surface of the target cell, through its interaction with the phagocyte receptor, LRP. In reality, however, only apoptotic cells are engulfed, apparently because their surface ligand CD47 is prevented from activating the inhibitory phagocyte receptor SIRP alpha.

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页码：1161 / 1163

页数：3

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