Current Radiotherapy Considerations for Nasopharyngeal Carcinoma

被引:26
|
作者
Ng, Wai Tong [1 ,2 ,3 ]
Chow, James C. H. [4 ]
Beitler, Jonathan J. [5 ]
Corry, June [6 ]
Mendenhall, William [7 ]
Lee, Anne W. M. [1 ,2 ]
Robbins, K. Thomas [8 ]
Nuyts, Sandra [9 ]
Saba, Nabil F. [10 ]
Smee, Robert [11 ]
Stokes, William A. [12 ]
Strojan, Primoz [13 ]
Ferlito, Alfio
机构
[1] Univ Hong Kong, Shenzhen Hosp, Clin Oncol Ctr, Shenzhen 518009, Peoples R China
[2] Univ Hong Kong, Shenzhen Hosp, Shenzhen Key Lab Canc Metastasis & Personalized Th, Shenzhen 518009, Peoples R China
[3] Univ Hong Kong, Li Ka Shing Fac Med, Dept Clin Oncol, Hong Kong, Peoples R China
[4] Queen Elizabeth Hosp, Dept Clin Oncol, Hong Kong, Peoples R China
[5] Knox Cty Hlth Clin, Rockland, ME 04841 USA
[6] St Vincents Hosp, Div Radiat Oncol, GenesisCare Radiat Oncol, Melbourne, Vic 3065, Australia
[7] Univ Florida, Dept Radiat Oncol, Coll Med, Gainesville, FL 32610 USA
[8] Southern Illinois Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Springfield, IL 62794 USA
[9] Univ Leuven, KU Leuven, Univ Hosp Leuven, Dept Radiat Oncol, B-3000 Leuven, Belgium
[10] Emory Univ, Winship Canc Inst, Dept Hematol & Med Oncol, Sch Med, Atlanta, GA 30322 USA
[11] Prince Wales Canc Ctr, Dept Radiat Oncol, Sydney, NSW 2031, Australia
[12] Emory Univ, Winship Canc Inst, Dept Radiat Oncol, Sch Med, Atlanta, GA 30322 USA
[13] Inst Oncol, Dept Radiat Oncol, Ljubljana 1000, Slovenia
关键词
nasopharyngeal cancer; radiotherapy; target delineation; adaptive planning; artificial intelligence; particle therapy; INTENSITY-MODULATED RADIOTHERAPY; CLINICAL TARGET VOLUME; LYMPH-NODE DISTRIBUTION; QUALITY-OF-LIFE; RADIATION-THERAPY; ARTIFICIAL-INTELLIGENCE; INDUCTION CHEMOTHERAPY; TREATMENT OUTCOMES; PROTON THERAPY; NCIC CTG;
D O I
10.3390/cancers14235773
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Simple Summary Nasopharyngeal carcinoma (NPC) is commonly treated using high-dose radiotherapy. Careful radiotherapy planning is crucial for the eradication of cancer cells while avoiding injuries to normal structures. This balance is often delicate given the complex anatomic location in which NPC is situated. This article highlights the considerations, practical pearls, and recent advances in the precise delivery of radiotherapy in NPC patients. Radiotherapy is the primary treatment modality for nasopharyngeal carcinoma (NPC). Successful curative treatment requires optimal radiotherapy planning and precise beam delivery that maximizes locoregional control while minimizing treatment-related side effects. In this article, we highlight considerations in target delineation, radiation dose, and the adoption of technological advances with the aim of optimizing the benefits of radiotherapy in NPC patients.
引用
收藏
页数:15
相关论文
共 50 条
  • [31] Automated Patient-specific Quality Assurance for Automated Segmentation of Organs at Risk in Nasopharyngeal Carcinoma Radiotherapy
    Wang, Yixuan
    Hu, Jiang
    Chen, Lixin
    Zhang, Dandan
    Zhu, Jinhan
    CANCER CONTROL, 2025, 32
  • [32] Radiotherapy-Related Quality of Life in Nasopharyngeal Carcinoma Patients: A Systematic Review and Meta-Analysis
    Chen, Kai
    Cai, Yuan
    Jiang, Luyun
    Tian, Li
    ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY HEAD AND NECK SURGERY, 2024, : 200 - 210
  • [33] TECHNICAL AND DOSIMETRIC CONSIDERATIONS IN MULTI-ISOCENTER INTENSITY MODULATED RADIOTHERAPY FOR NASOPHARYNGEAL CARCINOMA WITH SMALL MULTILEAF COLLIMATOR
    Jin Xiance
    Wu Shixiu
    Yu Jianyi
    Yi Jinling
    MEDICAL DOSIMETRY, 2009, 34 (01) : 9 - 15
  • [34] Nasopharyngeal granulomatous mass after radiotherapy for nasopharyngeal carcinoma
    Yang, Lu
    Li, Houyong
    Wang, Huan
    Zhang, Huankang
    Wang, Shuyi
    Fry, Allison N.
    Han, Wade W.
    Wang, Dehui
    AURIS NASUS LARYNX, 2016, 43 (03) : 330 - 335
  • [35] Nasopharyngeal carcinoma: an evolving paradigm
    Wong, Kenneth C. W.
    Hui, Edwin P.
    Lo, Kwok-Wai
    Lam, Wai Kei Jacky
    Johnson, David
    Li, Lili
    Tao, Qian
    Chan, Kwan Chee Allen
    To, Ka-Fai
    King, Ann D.
    Ma, Brigette B. Y.
    Chan, Anthony T. C.
    NATURE REVIEWS CLINICAL ONCOLOGY, 2021, 18 (11) : 679 - 695
  • [36] The quality of life in nasopharyngeal carcinoma radiotherapy: A longitudinal study
    Kan, Yajing
    Yang, Shuang
    Wu, Xueting
    Wang, Siqi
    Li, Xueyu
    Zhang, Fangyuan
    Wang, Peiguo
    Zhao, Jing
    ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING, 2023, 10 (07)
  • [37] Prognostic significance of wait time for radical radiotherapy in locoregionally advanced nasopharyngeal carcinoma
    Jiang, Yu-Ting
    Chen, Kai-Hua
    Yang, Jie
    Liang, Zhong-Guo
    Qu, Song
    Li, Ling
    Zhu, Xiao-Dong
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2022, 44 (05): : 1182 - 1191
  • [38] Nomograms incorporating primary tumor response at mid-radiotherapy to predict survival in locoregionally advanced nasopharyngeal carcinoma
    Liu, Xixi
    Huang, Jing
    Qin, You
    Zhang, Zhanjie
    Wu, Bian
    Yang, Kunyu
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2023, 45 (08): : 1922 - 1933
  • [39] Robotic stereotactic body radiotherapy for recurrent nasopharyngeal carcinoma
    Uysal, Emre
    Aksaray, Ferdi
    Dincer, Selvi
    Altin, Suleyman
    INDIAN JOURNAL OF CANCER, 2023, 60 (03) : 353 - 358
  • [40] Symptom clusters in patients with nasopharyngeal carcinoma during radiotherapy
    Xiao, Wenli
    Chan, Carmen W. H.
    Fan, Yuying
    Leung, Doris Y. P.
    Xia, Weixiong
    He, Yan
    Tang, Linquan
    EUROPEAN JOURNAL OF ONCOLOGY NURSING, 2017, 28 : 7 - 13