Is mandatory screening for obstructive sleep apnea with polysomnography in all severely obese patients indicated?

被引:30
作者
Carneiro, Glaucia [2 ]
Florio, Ronaldo T. B. [1 ]
Zanella, Maria Teresa [2 ]
Pradella-Hallinan, Marcia [1 ]
Ribeiro-Filho, Fernando Flexa [2 ]
Tufik, Sergio [1 ]
Togeiro, Sonia Maria [1 ]
机构
[1] Univ Fed Sao Paulo, Sleep Disorders Ctr, Dept Psychobiol, Sao Paulo, Brazil
[2] Univ Fed Sao Paulo, Dept Med, Div Endocrinol, Sao Paulo, Brazil
基金
巴西圣保罗研究基金会;
关键词
Sleep apnea; Severe obesity; Polysomnography; BREATHING DISORDERS; DAYTIME SLEEPINESS; GENDER-DIFFERENCES; GASTRIC BYPASS; PREVALENCE; PREDICTORS; SEVERITY; WOMEN;
D O I
10.1007/s11325-010-0468-7
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The study aims to assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among severely obese patients evaluated for bariatric surgery. Polysomnography recordings were performed in consecutive patients undergoing Roux-en-Y gastric bypass from January 2004 to January 2007. Sleep apnea was noted as present or absent and graded from mild to severe according to the apnea/hypopnea index. Patient gender, age, weight, height, body mass index, neck circumference, and waist circumference were recorded. A total of 132 patients were included in the study group, and 85 patients had a confirmed diagnosis of OSA (64.4%). The prevalence of OSA was 55.7% in female and 77.4% in male. The prevalence of moderate or severe sleep apnea was higher in males (71.6%) than in females (31.6%). In OSA patients, body mass index (p = 0.020), neck circumference (p < 0.001), and age (p = 0.003) were higher as compared with obese patients without OSA, whereas no differences were found in waist circumference between groups. After multiple regression analysis, body mass index, age, and male gender were independent predictors of sleep apnea. In the female group, age greater than 49 years was the only significant predictor of moderate or severe OSA (odds ratio 5.42 (95% confidence interval 1.61-18.1); p = 0.006). Males and females with age greater than 49 years are at greatest risk for OSA. Preoperative sleep studies should be mandatory in this group of severely obese patients.
引用
收藏
页码:163 / 168
页数:6
相关论文
共 38 条
[1]   Postoperative hypoxemia in morbidly obese patients with and without obstructive sleep apnea undergoing laparoscopic bariatric surgery [J].
Ahmad, Shireen ;
Nagle, Alexander ;
McCarthy, Robert J. ;
Fitzgerald, Paul C. ;
Sullivan, John T. ;
Prystowsky, Jay .
ANESTHESIA AND ANALGESIA, 2008, 107 (01) :138-143
[2]  
Amer Soc Anesthesiologists, 2006, ANESTHESIOLOGY, V104, P1081
[3]  
Bell Robert L, 2005, Anesthesiol Clin North Am, V23, P493, DOI 10.1016/j.atc.2005.03.007
[4]  
Benumof Jonathan L, 2004, Curr Opin Anaesthesiol, V17, P21, DOI 10.1097/00001503-200402000-00005
[5]   Prevalence of sleep-disordered breathing in women - Effects of gender [J].
Bixler, EO ;
Vgontzas, AN ;
Lin, HM ;
Ten Have, T ;
Rein, J ;
Vela-Bueno, A ;
Kales, A .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (03) :608-613
[6]  
BONNET MH, 1992, SLEEP, V15, P526
[7]   Bariatric surgery: A systematic review and meta-analysis [J].
Buchwald, H ;
Avidor, Y ;
Braunwald, E ;
Jensen, MD ;
Pories, W ;
Fahrbach, K ;
Schoelles, K .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (14) :1724-1737
[8]  
Caplan RA, 2003, ANESTHESIOLOGY, V98, P1269
[9]   BARIATRIC SURGERY IN MORBIDLY OBESE SLEEP-APNEA PATIENTS - SHORT-TERM AND LONG-TERM FOLLOW-UP [J].
CHARUZI, I ;
LAVIE, P ;
PEISER, J ;
PELED, R .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1992, 55 (02) :594-596
[10]   Prevalence and severity of sleep apnea in a group of morbidly obese patients [J].
Daltro, Carla ;
Gregorio, Paloma Baiardi ;
Alves, Erivaldo ;
Abreu, Mauricio ;
Bomfim, Daniel ;
Chicourel, Maria Helena ;
Araujo, Leila ;
Cotrim, Helma P. .
OBESITY SURGERY, 2007, 17 (06) :809-814