Photodynamic therapy of intraductal papillary mucinous neoplasm

被引：16

作者：

Topazian, M. ^{[1
]}

Zhong, N. ^{[2
]}

Baron, T. H. ^{[1
]}

Vege, S. S. ^{[1
]}

Wang, K. K. ^{[1
]}

机构：

[1] Mayo Clin, Dept Internal Med, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA

[2] Shandong Univ, Qilu Hosp, Dept Gastroenterol, Jinan, Shandong, Peoples R China

来源：

ENDOSCOPY | 2012年 / 44卷 / 02期

关键词：

PANCREAS; CHOLANGIOCARCINOMA; ULTRASONOGRAPHY; MALIGNANCY; MANAGEMENT; CONSENSUS; SURVIVAL; CANCER; TUMORS; DUCT;

D O I：

10.1055/s-0031-1291539

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Intraductal papillary mucinous neoplasm (IPMN) of the main pancreatic duct is usually treated by surgical excision of the affected pancreas. Non-operative ablative therapies have not been described. We treated IPMN of the pancreatic duct with photodynamic therapy (PDT) in a patient who was a poor operative candidate. Porfimer sodium was administered intravenously, and laser light was delivered by a diffusing catheter placed in the pancreatic duct during endoscopic retrograde cholangiopancreatography (ERCP). Imaging and biopsy findings of IPMN resolved after PDT, and symptoms also resolved. Metastatic cancer was diagnosed 2 years after PDT had been initiated. Pancreatic PDT was well tolerated in this case, and may be a therapeutic option for selected patients with IPMN of the main pancreatic duct.

引用

页码：214 / 216

页数：3

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