Photodynamic therapy of intraductal papillary mucinous neoplasm

被引：16
|
作者：
Topazian, M. [1 ]
Zhong, N. [2 ]
Baron, T. H. [1 ]
Vege, S. S. [1 ]
Wang, K. K. [1 ]
机构：
[1] Mayo Clin, Dept Internal Med, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA
[2] Shandong Univ, Qilu Hosp, Dept Gastroenterol, Jinan, Shandong, Peoples R China
来源：
ENDOSCOPY | 2012年 / 44卷 / 02期
关键词：
PANCREAS; CHOLANGIOCARCINOMA; ULTRASONOGRAPHY; MALIGNANCY; MANAGEMENT; CONSENSUS; SURVIVAL; CANCER; TUMORS; DUCT;
D O I：
10.1055/s-0031-1291539
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Intraductal papillary mucinous neoplasm (IPMN) of the main pancreatic duct is usually treated by surgical excision of the affected pancreas. Non-operative ablative therapies have not been described. We treated IPMN of the pancreatic duct with photodynamic therapy (PDT) in a patient who was a poor operative candidate. Porfimer sodium was administered intravenously, and laser light was delivered by a diffusing catheter placed in the pancreatic duct during endoscopic retrograde cholangiopancreatography (ERCP). Imaging and biopsy findings of IPMN resolved after PDT, and symptoms also resolved. Metastatic cancer was diagnosed 2 years after PDT had been initiated. Pancreatic PDT was well tolerated in this case, and may be a therapeutic option for selected patients with IPMN of the main pancreatic duct.
引用
收藏
页码：214 / 216
页数：3
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