Synthesis and Antibacterial Activity Investigation of Novel Cuprous Oxide-Graphene Oxide Nanocomposites

被引：6
作者：
Huang, Hua [1 ,2 ]
Velmurugan, Murugan [2 ]
Kesavan, Manibalan [2 ]
Zhang, Qiang [2 ]
Lu, Xinling [1 ,2 ]
Wang, Yong [1 ]
Lin, Jin-Ming [2 ]
机构：
[1] Tianjin Univ, Sch Sci, Dept Chem, Tianjin 300075, Peoples R China
[2] Tsinghua Univ, MOE Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing Key Lab Microanalyt Methods & Instrumenta, Dept Chem, Beijing 100084, Peoples R China
来源：
CHEMISTRY LETTERS | 2020年 / 49卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Cuprous oxide; Graphene oxide; Antibacterial; ANTIMICROBIAL ACTIVITY; ANTIBIOTIC-RESISTANCE; BIOFOULING CONTROL; NANOPARTICLES; EFFICIENT; SILVER; IMMOBILIZATION; NANOTECHNOLOGY; ANTIFUNGAL; IMPACT;
D O I：
10.1246/cl.200128
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Due to the increasing resistance of pathogens to antibiotics, novel antibacterial nanocomposite materials have been attracting increasing research interest. Herein, we report a facile synthetic method for a novel highly antibacterial nanocomposite based on graphene oxide (GO) nanosheets decorated with cuprous oxide by a two-step method. The as-prepared nanocomposites were comprehensively characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), energy-dispersive X-ray (EDX) spectroscopy, field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). The nanocomposite was investigated for antibacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) using the medium dilution method and the disc diffusion method. The results showed that the synthesized Cu2O-GO has good antibacterial activities. At the nanocomposites concentration of 100 mu g/mL, the inhibition rate against E. coli reached 68%, while the inhibition rate against. S. aureus reached 32%.
引用
收藏
页码：693 / 696
页数：4
相关论文
共 43 条
[1]   Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance [J].
Abouelhassan, Yasmeen ;
Garrison, Aaron T. ;
Yang, Hongfen ;
Chavez-Riveros, Alejandra ;
Burch, Gena M. ;
Huigens, Robert W., III .
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 62 (17) :7618-7642
[2]   A new large - Scale synthesis of magnesium oxide nanowires: Structural and antibacterial properties [J].
Al-Hazmi, Faten ;
Alnowaiser, Fowzia ;
Al-Ghamdi, A. A. ;
Al-Ghamdi, Attieh A. ;
Aly, M. M. ;
Al-Tuwirqi, Reem M. ;
El-Tantawy, Farid .
SUPERLATTICES AND MICROSTRUCTURES, 2012, 52 (02) :200-209
[3]   Towards industrial applications of graphene electrodes [J].
Bae, Sukang ;
Kim, Sang Jin ;
Shin, Dolly ;
Ahn, Jong-Hyun ;
Hong, Byung Hee .
PHYSICA SCRIPTA, 2012, T146
[4]   Antibacterial applications of α-Fe2O3/Co3O4 nanocomposites and study of their structural, optical, magnetic and cytotoxic characteristics [J].
Bhushan, Mayank ;
Kumar, Yogesh ;
Periyasamy, Latha ;
Viswanath, Annamraju Kasi .
APPLIED NANOSCIENCE, 2018, 8 (1-2) :137-153
[5]   The growing role of nanotechnology in combating infectious disease [J].
Blecher, Karin ;
Nasir, Adnan ;
Friedman, Adam .
VIRULENCE, 2011, 2 (05) :395-401
[6]   Waves of resistance: Staphylococcus aureus in the antibiotic era [J].
Chambers, Henry F. ;
DeLeo, Frank R. .
NATURE REVIEWS MICROBIOLOGY, 2009, 7 (09) :629-641
[7]   Efficient Bacterial Inactivation by Transition Metal Catalyzed Auto-Oxidation of Sulfite [J].
Chen, Long ;
Tang, Min ;
Chen, Chuan ;
Chen, Mingguang ;
Luo, Kai ;
Xu, Jing ;
Zhou, Danna ;
Wu, Feng .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 51 (21) :12663-12671
[8]   Copper nanoparticle/polymer composites with antifungal and bacteriostatic properties [J].
Cioffi, N ;
Torsi, L ;
Ditaranto, N ;
Tantillo, G ;
Ghibelli, L ;
Sabbatini, L ;
Bleve-Zacheo, T ;
D'Alessio, M ;
Zambonin, PG ;
Traversa, E .
CHEMISTRY OF MATERIALS, 2005, 17 (21) :5255-5262
[9]   Microbial biofilms: from ecology to molecular genetics [J].
Davey, ME ;
O'toole, GA .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2000, 64 (04) :847-+
[10]   Graphene oxide decorated with zinc oxide nanoflower, silver and titanium dioxide nanoparticles: fabrication, characterization, DNA interaction, and antibacterial activity [J].
El-Shafai, Nagi ;
El-Khouly, Mohamed E. ;
El-Kemary, Maged ;
Ramadan, Mohamed ;
Eldesoukey, Ibrahim ;
Masoud, Mamdouh .
RSC ADVANCES, 2019, 9 (07) :3704-3714
12345