Extracellular Vesicles: A Prevalent Tool for Microbial Gene Delivery?

被引：7

作者：

Ben-Hur, Sharon ^{[1
]}

Biton, Mirit ^{[1
]}

Regev-Rudzki, Neta ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Biomol Sci, Fac Biochem, Rehovot, Israel

来源：

PROTEOMICS | 2019年 / 19卷 / 1-2期

基金：

以色列科学基金会; 欧洲研究理事会;

关键词：

extracellular vesicles; horizontal gene transfer; MEMBRANE-VESICLES; MEDIATED TRANSFER; DNA; EXOSOMES; DEOXYRIBONUCLEASE; IDENTIFICATION; COMMUNICATION; MICROVESICLES; BIOGENESIS; BACTERIA;

D O I：

10.1002/pmic.201800170

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Genetic plasticity of prokaryotic microbial communities is largely dependent on the ongoing exchange of genetic determinants by Horizontal Gene Transfer (HGT). HGT events allow beneficial genetic transitions to occur throughout microbial life, thus promoting adaptation to changing environmental conditions. Here, the significance of secreted vesicles in mediating HGT between microorganisms is discussed, while focusing on the benefits gained by vesicle-mediated gene delivery and its occurrence under different environmental cues. The potential use of secreted DNA-harboring vesicles as a mechanism of currently unresolved HGT events in eukaryotic microbes is further discussed.

引用

页数：4

共 53 条

[1] Proteus mirabilis clinical isolate harbouring a new variant of Salmonella genomic island 1 containing the multiple antibiotic resistance region [J].

Ahmed, Ashraf M. ;

Hussein, Amjad I. A. ;

Shimamoto, Tadashi .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2007, 59 (02) :184-190

[2] A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms [J].

Allesen-Holm, M ;

Barken, KB ;

Yang, L ;

Klausen, M ;

Webb, JS ;

Kjelleberg, S ;

Molin, S ;

Givskov, M ;

Tolker-Nielsen, T .

MOLECULAR MICROBIOLOGY, 2006, 59 (04) :1114-1128

[3] Bacterial Vesicles in Marine Ecosystems [J].

Biller, Steven J. ;

Schubotz, Florence ;

Roggensack, Sara E. ;

Thompson, Anne W. ;

Summons, Roger E. ;

Chisholm, Sallie W. .

SCIENCE, 2014, 343 (6167) :183-186

[4]

Bitto N. J., 2017, SCI REP, V7, P1

[5] Contribution of vesicle-protected extracellular DNA to horizontal gene transfer in Thermus spp. [J].

Blesa, Alba ;

Berenguer, Jose .

INTERNATIONAL MICROBIOLOGY, 2015, 18 (03) :177-187

[6] Mechanism of retarded DNA degradation and prokaryotic origin of DNases in nonsterile soils [J].

Blum, SAE ;

Lorenz, MG ;

Wackernagel, W .

SYSTEMATIC AND APPLIED MICROBIOLOGY, 1997, 20 (04) :513-521

[7] Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi [J].

Brown, Lisa ;

Wolf, Julie M. ;

Prados-Rosales, Rafael ;

Casadevall, Arturo .

NATURE REVIEWS MICROBIOLOGY, 2015, 13 (10) :620-630

[8] Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases [J].

Campos, Joao Henrique ;

Soares, Rodrigo Pedro ;

Ribeiro, Kleber ;

Andrade, Andre Cronemberger ;

Batista, Wagner Luiz ;

Torrecilhas, Ana Claudia .

JOURNAL OF IMMUNOLOGY RESEARCH, 2015, 2015

[9] Acinetobacter baumannii transfers the blaNDM-1 gene via outer membrane vesicles i transfers the blaNDM-1 gene via outer membrane vesicles [J].

Chatterjee, Somdatta ;

Mondal, Ayan ;

Mitra, Shravani ;

Basu, Sulagna .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2017, 72 (08) :2201-2207

[10] Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections [J].

Coakley, Gillian ;

Maizels, Rick M. ;

Buck, Amy H. .

TRENDS IN PARASITOLOGY, 2015, 31 (10) :477-489

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