Study on fungitoxic 3-amino-2-piperidinone-containing lipids: Revised structure of cepaciamide A and structural determination of its closely related lipid, cepaciamide B

被引：9

作者：

Toshima, H ^{[1
]}

Maru, K ^{[1
]}

Jiao, Y ^{[1
]}

Yoshihara, T ^{[1
]}

Ichihara, A ^{[1
]}

机构：

[1] Hokkaido Univ, Fac Agr, Dept Biosci & Chem, Sapporo, Hokkaido 0608589, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(98)02493-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structure of cepaciamide A was revised to be (3R,3'S,2"S,11"S,12"R)-3-[3'-(2"-hydroxy-11", 12"-methyleneoctadecanoyloxy)hexadecamido]-2-piperidinone with respect to the absolute configuration of the C-3'- and C-2"-positions and the position of the cyclopropane ring by using synthetic methods. The structure of cepaciamide B was also determined to be (3R,3'S,2"S,11"Z)-3-[3'-(2"-hydroxy-11"-octadecenoyloxy)hexadecamido]-2-piperidinone. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：935 / 938

页数：4