Tubulointerstitial Nephritis

被引：12
作者：
Ruebner, Rebecca L. [1 ]
Fadrowski, Jeffrey J. [1 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Dept Pediat, Div Nephrol, 200 North Wolfe St,Room 3055, Baltimore, MD 21287 USA
来源：
PEDIATRIC CLINICS OF NORTH AMERICA | 2019年 / 66卷 / 01期
关键词：
Tubulointerstitial nephritis; Acute interstitial nephritis; Acute kidney injury; Tubulointerstitial nephritis with uveitis; ACUTE INTERSTITIAL NEPHRITIS; INFLAMMATORY-BOWEL-DISEASE; EXTRAINTESTINAL MANIFESTATION; UVEITIS; MUTATIONS; NEPHROPATHY; EXPRESSION; DIAGNOSIS; CHILDREN; SPECTRUM;
D O I：
10.1016/j.pcl.2018.08.009
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Tubulointerstitial nephritis (TIN) is a cause of acute kidney injury in children characterized histologically by an inflammatory cell infiltrate in the kidney interstitium. The most common causes of TIN in children include medications, infections, inflammatory disorders, and genetic conditions. TIN typically presents with nonoliguric acute kidney injury and may be associated with systemic symptoms, including fever, rash, and eosinophilia. The long-term prognosis is generally favorable, with full kidney recovery; however, some patients may develop progressive chronic kidney disease. Immunosuppressive therapy may be indicated for severe or prolonged disease.
引用
收藏
页码：111 / +
页数：10
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