How many people have sickle cell disease in the UK?

被引：47

作者：

Dormandy, Elizabeth ^{[1
]}

James, John ^{[1
]}

Inusa, Baba ^{[2
]}

Rees, David ^{[3
,4
]}

机构：

[1] Sickle Cell Soc, 54 Stn Rd, London NW10 4UA, England

[2] Guys & St Thomas NHS Fdn Trust, Evelina London Childrens Healthcare, London, England

[3] Kings Coll London, Dept Mol Haematol, London, England

[4] Kings Coll NHS Fdn Trust, London, England

来源：

JOURNAL OF PUBLIC HEALTH | 2018年 / 40卷 / 03期

关键词：

blood and immune disorders; epidemiology; genetics; CHILDREN; ENGLAND; TRENDS;

D O I：

10.1093/pubmed/fdx172

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background Sickle Cell Disease (SCD) is now one of the most common serious genetic condition in England. There is no reliable estimate of the total number of people living with SCD in the UK, to support commissioners and providers of services for people with SCD. Aim To obtain reliable data on the total number of people living with SCD in the UK in 2016. Method Information was requested from all national databases known to hold information on the number of people living with SCD in the UK. The information from each data source was first reviewed to estimate likely inaccuracies and then combined to provide a best estimate of people living with SCD in the UK. Conclusion This process indicated there are are about 14000 people living with SCD in the UK. This is equivalent to 1 in 4600 people.

引用

页码：E291 / E295

页数：5

共 7 条

[1] Trends in hospital admissions for sickle cell disease in England, 2001/02-2009/10 [J].

AlJuburi, Ghida ;

Laverty, Anthony A. ;

Green, Stuart A. ;

Phekoo, Karen J. ;

Banarsee, Ricky ;

Okoye, N. V. Ogo ;

Bell, Derek ;

Majeed, Azeem .

JOURNAL OF PUBLIC HEALTH, 2012, 34 (04) :570-576

[2] Implementing neonatal screening for haemoglobinopathies in the Netherlands [J].

Bouva, Marelle J. ;

Mohrmann, Karin ;

Brinkman, Henri B. J. M. ;

Kemper-Proper, Evelien A. ;

Elvers, Bert ;

Loeber, J. Gerard ;

Verheul, Francesco E. A. M. ;

Giordano, Piero C. .

JOURNAL OF MEDICAL SCREENING, 2010, 17 (02) :58-65

[3] Newborn screening for sickle cell disease in Brazil: the Campinas experience [J].

Brandelise, S ;

Pinheiro, V ;

Gabetta, CS ;

Hambleton, I ;

Serjeant, B ;

Serjeant, G .

CLINICAL AND LABORATORY HAEMATOLOGY, 2004, 26 (01) :15-19

[4] Global Burden of Sickle Cell Anaemia in Children under Five, 2010-2050: Modelling Based on Demographics, Excess Mortality, and Interventions [J].

Piel, Frederic B. ;

Hay, Simon I. ;

Gupta, Sunetra ;

Weatherall, David J. ;

Williams, Thomas N. .

PLOS MEDICINE, 2013, 10 (07)

[5] Global migration and the changing distribution of sickle haemoglobin: a quantitative study of temporal trends between 1960 and 2000 [J].

Piel, Frederic B. ;

Tatem, Andrew J. ;

Huang, Zhuojie ;

Gupta, Sunetra ;

Williams, Thomas N. ;

Weatherall, David J. .

LANCET GLOBAL HEALTH, 2014, 2 (02) :E80-E89

[6] Improved survival of children and adolescents with sickle cell disease [J].

Quinn, Charles T. ;

Rogers, Zora R. ;

McCavit, Timothy L. ;

Buchanan, George R. .

BLOOD, 2010, 115 (17) :3447-3452

[7] Clinical outcomes in children with sickle cell disease living in England: a neonatal cohort in East London [J].

Telfer, Paul ;

Coen, Pietro ;

Chakravorty, Subarna ;

Wilkey, Olu ;

Evans, Jane ;

Newell, Heather ;

Smalling, Beverley ;

Amos, Roger ;

Stephens, Adrian ;

Rogers, David ;

Kirkham, Fenella .

HAEMATOLOGICA, 2007, 92 (07) :905-912

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