Synthesis and aggregation behaviour of a new sultaine surfactant

被引:18
作者
De Maria, Paolo [1 ]
Fontana, Antonella [1 ]
Siani, Gabriella [1 ]
D'Aurizio, Eleonora [1 ]
Cerichelli, Giorgio [2 ]
Chiarini, Marco [3 ]
Angelini, Guido [1 ]
Gasbarri, Carla [1 ]
机构
[1] Univ G DAnnunzio, Dipartimento Sci Farmaco, I-66013 Chieti, Italy
[2] Univ Aquila, Dipartimento Chim Ingn Chim & Mat, I-67010 Laquila, Italy
[3] Univ Teramo, Dipartimento Sci Alimenti, I-64023 Mosciano Sant Angelo, Teramo, Italy
关键词
Surfactant; Vesicles; CVC; Kinetics; Fluorescence; DIDODECYLDIMETHYLAMMONIUM BROMIDE; NILE RED; MULTILAMELLAR VESICLES; CHAIN SURFACTANTS; AQUEOUS-SOLUTIONS; MICELLAR SYSTEMS; PHASE-BEHAVIOR; LAMELLAR; WATER; FLUORESCENCE;
D O I
10.1016/j.colsurfb.2011.05.003
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The aggregation properties of a new sultaine surfactant have been studied in buffered aqueous solution at pH 7.4 under controlled condition of osmolarity. Spontaneously formed sultaine vesicles with a mean diameter of about 1 mu m can be observed by optical microscopy. The phase behaviour of the surfactant has been investigated by differential scanning calorimetry (DSC) and Nile Red fluorescence. Two critical vesicular concentrations (CVC(1) and CVC(2)) have been fluorimetrically measured, by using pyrene and Nile Red as the fluorescent probes. The two populations of vesicles behave differently as a consequence of their size. The stability of extruded large unilamellar vesicles (LUV) formed slightly above the CVC(1) has been evaluated in the temperature range 25-75 degrees C by following the rate of spontaneous release of entrapped 5(6)-carboxyfluorescein (CF). The stability of the same vesicles at 70 degrees C has also been investigated under osmotic stress obtained by adding NaCl or sucrose to the bulk solution. At a sultaine concentration above the CVC(2) LUV tend to associate and form stable larger closely packed aggregates as suggested by Dynamic Laser Light Scattering and rheological measurements. (C) 2011 Elsevier B.V. All rights reserved.
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页码:73 / 78
页数:6
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