Bullous Systemic Lupus Erythematosus

被引：26

作者：

Sebaratnam, Deshan F. ^{[1
]}

Murrell, Dedee F. ^{[1
]}

机构：

[1] Univ New S Wales, St George Hosp, Dept Dermatol, Sydney, NSW 2217, Australia

来源：

DERMATOLOGIC CLINICS | 2011年 / 29卷 / 04期

关键词：

Systemic lupus erythematosus; Vesiculobullous skin disease; Type VII collagen; EPIDERMOLYSIS-BULLOSA; VII COLLAGEN; REVISED CRITERIA; ERUPTION; AUTOANTIBODIES; COEXISTENCE; COMPONENTS; DISEASE; ANTIGEN; PATIENT;

D O I：

10.1016/j.det.2011.06.002

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Bullous systemic lupus erythematosus (BSLE) is a rare bullous dermatosis in patients with systemic lupus erythematosus. It is characterized by clinical and histologic features, resembling either bullous pemphigoid or dermatitis herpetiformis, and a heterogeneous immunologic profile, characterized by autoimmunity to components of type VII collagen, much like epidermolysis bullosa acquisita. As understanding of the pathology of this interesting dermatologic condition has evolved, so too have criteria and profiling of BSLE. The distinct clinical, histologic, and immunologic features of BSLE represent a unique bullous disease phenotype.

引用

页码：649 / +

页数：6

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