mRNA export: Travelling with DEAD box proteins

被引：57
作者：
Linder, P
Stutz, F
机构：
[1] Inst Microbiol, CH-1011 Lausanne, Switzerland
[2] Ctr Med Univ Geneva, Dept Biochim Med, CH-1211 Geneva 4, Switzerland
来源：
CURRENT BIOLOGY | 2001年 / 11卷 / 23期
关键词：
D O I：
10.1016/S0960-9822(01)00574-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent studies have shown that the putative RNA helicase protein UAP56 and its yeast homologue Sub2p are not only involved in pre-mRNA splicing but also required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene.
引用
收藏
页码：R961 / R963
页数：3
相关论文
共 26 条
  • [1] Pre-mRNA processing factors are required for nuclear export
    Brodsky, AS
    Silver, PA
    [J]. RNA, 2000, 6 (12) : 1737 - 1749
  • [2] ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCR alpha enhancer function
    Bruhn, L
    Munnerlyn, A
    Grosschedl, R
    [J]. GENES & DEVELOPMENT, 1997, 11 (05) : 640 - 653
  • [3] Unwinding RNA in Saccharomyces cerevisiae:: DEAD-box proteins and related families
    de la Cruz, J
    Kressler, D
    Linder, P
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1999, 24 (05) : 192 - 198
  • [4] High-copy-number expression of Sub2p, a member of the RNA helicase superfamily, suppresses hpr1-mediated genomic instability
    Fan, HY
    Merker, RJ
    Klein, HL
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (16) : 5459 - 5470
  • [5] U2AF(65) recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction
    Fleckner, J
    Zhang, M
    Valcarcel, J
    Green, MR
    [J]. GENES & DEVELOPMENT, 1997, 11 (14) : 1864 - 1872
  • [6] The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila
    Gatfield, D
    Le Hir, H
    Schmitt, C
    Braun, IC
    Köcher, T
    Wilm, M
    Izaurralde, E
    [J]. CURRENT BIOLOGY, 2001, 11 (21) : 1716 - 1721
  • [7] Quality control of mRNA 3′-end processing is linked to the nuclear exosome
    Hilleren, P
    McCarthy, T
    Rosbash, M
    Parker, R
    Jensen, TH
    [J]. NATURE, 2001, 413 (6855) : 538 - 542
  • [8] The DECD box putative ATPase Sub2p is an early mRNA export factor
    Jensen, TH
    Boulay, J
    Rosbash, M
    Libri, D
    [J]. CURRENT BIOLOGY, 2001, 11 (21) : 1711 - 1715
  • [9] Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase
    Kistler, AL
    Guthrie, C
    [J]. GENES & DEVELOPMENT, 2001, 15 (01) : 42 - 49
  • [10] The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
    Le Hir, H
    Gatfield, D
    Izaurralde, E
    Moore, MJ
    [J]. EMBO JOURNAL, 2001, 20 (17) : 4987 - 4997
123