Gluten and IgA nephropathy: you are what you eat?

被引：12

作者：

Cheung, Chee Kay ^{[1
]}

Barratt, Jonathan ^{[1
]}

机构：

[1] Univ Leicester, Dept Infect Immun & Inflammat, Leicester, Leics, England

来源：

KIDNEY INTERNATIONAL | 2015年 / 88卷 / 02期

关键词：

CELIAC-DISEASE;

D O I：

10.1038/ki.2015.149

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Although extensively studied, the relationship between dietary antigens-in particular, gluten-and IgA nephropathy remains unclear. Using a double transgenic mouse model of IgA nephropathy that expresses both human IgA1 and human CD89, Papista et al. report that a gluten-free diet protects against the development of IgA deposition and glomerular injury, and that these events occur with the introduction of dietary gluten.

引用

页码：215 / 218

页数：5

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