Three cases of PR3-ANCA positive subacute endocarditis caused by attenuated bacteria (Propionibacterium, Gemella, and Bartonella) complicated with kidney injury

被引：15

作者：

Satake, Kenji ^{[1
]}

Ohsawa, Isao ^{[1
]}

Kobayashi, Noriyoshi ^{[1
]}

Osaki, Ken ^{[1
]}

Toyoda, Hitoe ^{[1
]}

Horikoshi, Satoshi ^{[1
]}

Tomino, Yasuhiko ^{[1
]}

机构：

[1] Juntendo Univ, Div Nephrol, Dept Internal Med, Fac Med,Bunkyo Ku, Tokyo 1138421, Japan

来源：

MODERN RHEUMATOLOGY | 2011年 / 21卷 / 05期

关键词：

PR3-ANCA; Infectious endocarditis; Acute kidney injury; Attenuated bacteria; Hypocomplementemia; ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODIES; PROSTHETIC VALVE ENDOCARDITIS; INFECTIVE ENDOCARDITIS; ACNES; ANCA; GLOMERULONEPHRITIS; MORBILLORUM; ANTIBODIES; DIAGNOSIS;

D O I：

10.1007/s10165-011-0434-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Subacute bacterial endocarditis (SBE) associated with antiproteinase-3 antineutrophil cytoplasmic antibodies (PR3-ANCA) has previously been reported in 10 cases of Streptococcus viridans and in 1 case of Escherichia faecalis infection. Most of these patients had hypocomplementemia and were positive for several auto-antibodies. The infections in most of these patients showed good responses to antibiotic treatment. We report three patients with ANCA-positive SBE, which was induced by attenuated slow-growing intracellular pathogens; these patients had severe complications, such as acute kidney injury, cerebral embolism, and aortic valve destruction.

引用

页码：536 / 541

页数：6

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