FOXA transcription factors determine the amplitude of glucocorticoid induction of tyrosine aminotransferase in mice

被引：1
|
作者：
Bryzgalov, L. O. [1 ]
Ershov, N. I. [1 ]
Ilnitskaya, S. I. [1 ]
机构：
[1] Russian Acad Sci, Siberian Div, Inst Cytol & Genet, Novosibirsk, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2007年 / 144卷 / 05期
基金：
俄罗斯基础研究基金会;
关键词：
FOXA transcription factors; aminoazo dyes; tyrosine aminotransferase; glucocorticoid induction;
D O I：
10.1007/s10517-007-0415-1
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
o-Aminoazotoluene was more potent than 3'-methyl-4-dimethylaminoazobenzene in modulating glucocorticoid induction of tyrosine aminotransferase and DNA-binding activity of FOXA (HNF3) in 12-day-old ICR mice. In adult animals, induction of tyrosine aminotransferase and FOXA activity were modulated by o-aminoazotoluene, while 3'-methyl-4-dimethylaminoazobenzene was ineffective. Our results suggest that FOXA proteins determine glucocorticoid induction of tyrosine aminotransferase in mice (similarly to rats).
引用
收藏
页码：722 / 724
页数：3
相关论文
共 50 条
  • [21] FACTORS AFFECTING PREMATURE INDUCTION OF TYROSINE AMINOTRANSFERASE IN FOETAL RAT LIVER
    HOLT, PG
    OLIVER, IT
    BIOCHEMICAL JOURNAL, 1968, 108 (02) : 333 - &
  • [22] EFFECT OF MOLYBDATE ON GLUCOCORTICOID RECEPTORS INVITRO AND ON THE INDUCTION OF TYROSINE AMINOTRANSFERASE ACTIVITY IN RAT-LIVER
    BARAMOVA, EN
    VAPTZAROVA, KI
    HAVEZOV, I
    ANGELOV, AM
    POPOV, PG
    DOKLADI NA BOLGARSKATA AKADEMIYA NA NAUKITE, 1984, 37 (06): : 819 - 822
  • [23] INTERACTION OF GLUCOCORTICOID HORMONES AND CYCLIC NUCLEOTIDES IN INDUCTION OF TYROSINE AMINOTRANSFERASE IN CULTURED HEPATOMA-CELLS
    GRANNER, DK
    LEE, A
    THOMPSON, EB
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1977, 252 (11) : 3891 - 3897
  • [24] MODULATION OF GLUCOCORTICOID INDUCTION OF TYROSINE AMINOTRANSFERASE GENE-EXPRESSION BY VARIATIONS IN CELL-DENSITY
    OSHIMA, H
    SIMONS, SS
    ENDOCRINOLOGY, 1992, 130 (04) : 2106 - 2112
  • [25] Species Specific Hepatocarcinogen Inhibition of the Glucocorticoid Induction of Tyrosine Aminotransferase Gene in Mouse and Rat Liver
    T. I. Merkulova
    K. Y. Kropachev
    O. A. Timofeeva
    G. V. Vasiliev
    S. I. Ilnitskaya
    Z. B. Levashova
    V. F. Kobzev
    V. I. Kaledin
    Biochemistry (Moscow), 2003, 68 : 520 - 528
  • [26] DIFFERENTIAL DYNAMICS OF RECEPTOR DOWN-REGULATION AND TYROSINE AMINOTRANSFERASE INDUCTION FOLLOWING GLUCOCORTICOID TREATMENT
    DUBOIS, DC
    XU, ZX
    MCKAY, L
    ALMON, RR
    PYSZCZNSKI, N
    JUSKO, WJ
    JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1995, 54 (5-6): : 237 - 243
  • [27] Species specific hepatocarcinogen inhibition of the glucocorticoid induction of tyrosine aminotransferase gene in mouse and rat liver
    Merkulova, T.I.
    Kropachev, K.Y.
    Timofeeva, O.A.
    Vasil'ev, G.V.
    Ilnitskaya, S.I.
    Levashova, Z.B.
    Kobzev, V.F.
    Kaledin, V.I.
    Biokhimiya, 2003, 68 (05): : 639 - 649
  • [28] Species specific hepatocarcinogen inhibition of the glucocorticoid induction of tyrosine aminotransferase gene in mouse and rat liver
    Merkulova, TI
    Kropachev, KY
    Timofeeva, OA
    Vasiliev, GV
    Ilnitskaya, SI
    Levashova, ZB
    Kobzev, VF
    Kaledin, VI
    BIOCHEMISTRY-MOSCOW, 2003, 68 (05) : 520 - 528
  • [29] ROLE OF TRANSCORTIN IN GLUCOCORTICOID MEDIATED ENZYME-INDUCTION - TYROSINE AMINOTRANSFERASE INDUCTION IN HEPATOMA TISSUE-CULTURE CELLS
    LIPPMAN, M
    THOMPSON, EB
    JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1974, 5 (05): : 461 - 465
  • [30] 2 REMOTE GLUCOCORTICOID RESPONSIVE UNITS INTERACT COOPERATIVELY TO PROMOTE GLUCOCORTICOID INDUCTION OF RAT TYROSINE AMINOTRANSFERASE GENE-EXPRESSION
    GRANGE, T
    ROUX, J
    RIGAUD, G
    PICTET, R
    NUCLEIC ACIDS RESEARCH, 1989, 17 (21) : 8695 - 8709
12345