Targeted drug delivery systems for bladder cancer therapy

被引:24
作者
Yu, Kun [1 ]
Liu, Meiping [1 ]
Dai, Hong [1 ]
Huang, Xiao [2 ]
机构
[1] Three Gorges Cent Hosp, Dept Urol Surg, Chongqing 404000, Peoples R China
[2] Tongren Univ, Sch Sports & Hlth Sci, Inst Nanomed & Biomat, Tongren 554300, Peoples R China
基金
中国国家自然科学基金;
关键词
Targeting strategy; Drug delivery system; Photodynamic therapy; Bladder cancer; INTRAVESICAL THERAPY; URINARY-BLADDER; NANOPARTICLES; CHEMOTHERAPY; DOXORUBICIN; STRATEGIES; ACID; RAT; CYTOTOXICITY; NANOCARRIERS;
D O I
10.1016/j.jddst.2020.101535
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Bladder cancer is a severe disease that threatens human health. The high recurrence rate and severe side-effects of traditional bladder cancer therapy require more efficient and higher targeting treatment. Drug delivery systems especially being endowed with the targeting property may provide a feasible means to solve such problems. Herein, we have reviewed the recent progress of the drug delivery systems aiming at bladder cancer therapy especially focusing on their targeting strategies. Additionally, we give some outlook of the design on targeting strategy for more effective anti-cancer applications.
引用
收藏
页数:5
相关论文
共 68 条
[1]   Poly - (L) - glutamic acid drug delivery system for the intravesical therapy of bladder cancer using WGA as targeting moiety [J].
Apfelthaler, C. ;
Anzengruber, M. ;
Gabor, F. ;
Wirth, M. .
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2017, 115 :131-139
[2]   A doxorubicin loaded colloidal delivery system for the intravesical therapy of non-muscle invasive bladder cancer using wheat germ agglutinin as targeter [J].
Apfelthaler, Christina ;
Skoll, Katharina ;
Ciola, Raphaela ;
Gabor, Franz ;
Wirth, Michael .
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2018, 130 :177-184
[3]   A lectin mediated delivery system for the intravesical treatment of bladder diseases using poly-(L)-glutamic acid as polymeric backbone [J].
Apfelthaler, Christina ;
Gassenbauer, Patrick ;
Weisse, Sandra ;
Gabor, Franz ;
Wirth, Michael .
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 111 :376-382
[4]   A Galactose Dendritic Silicon (IV) Phthalocyanine as a Photosensitizing Agent in Cancer Photodynamic Therapy [J].
Bispo, Mafalda ;
Pereira, Patricia M. R. ;
Setaro, Francesca ;
Salome Rodriguez-Morgade, M. ;
Fernandes, Rosa ;
Torres, Tomas ;
Tome, Joao P. C. .
CHEMPLUSCHEM, 2018, 83 (09) :855-860
[5]   Synthesis and biological evaluation of a Platinum(II)-c(RGDyK) conjugate for integrin-targeted photodynamic therapy [J].
Chatzisideri, T. ;
Thysiadis, S. ;
Katsamakas, S. ;
Dalezis, P. ;
Sigala, I. ;
Lazarides, T. ;
Nikolakaki, E. ;
Trafalis, D. ;
Gederaas, O. A. ;
Lindgren, M. ;
Sarli, V. .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 141 :221-231
[6]   Multifunctional nanoclusters of NaYF4:Yb3+,Er3+ upconversion nanoparticle and gold nanorod for simultaneous imaging and targeted chemotherapy of bladder cancer [J].
Cho, Suehyun K. ;
Su, Lih-Jen ;
Mao, Chenchen ;
Wolenski, Connor D. ;
Flaig, Thomas W. ;
Park, Wounjhang .
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2019, 97 :784-792
[7]  
DEHARVEN E, 1992, CANCER RES, V52, P3131
[8]   Transferrin-conjugated liposome targeting of photosensitizer AlPcS4 to rat bladder carcinoma cells [J].
Derycke, ASL ;
Kamuhabwa, A ;
Gijsens, A ;
Roskams, T ;
De Vos, D ;
Kasran, A ;
Huwyler, J ;
Missiaen, L ;
de Witte, PAM .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2004, 96 (21) :1620-1630
[9]   Targeting Folate Receptors to Treat Invasive Urinary Bladder Cancer [J].
Dhawan, Deepika ;
Ramos-Vara, Jose A. ;
Naughton, James F. ;
Cheng, Liang ;
Low, Philip S. ;
Rothenbuhler, Ryan ;
Leamon, Christopher P. ;
Parker, Nikki ;
Klein, Patrick J. ;
Vlahov, Iontcho R. ;
Reddy, Joseph A. ;
Koch, Michael ;
Murphy, Linda ;
Fourez, Lindsey M. ;
Stewart, Jane C. ;
Knapp, Deborah W. .
CANCER RESEARCH, 2013, 73 (02) :875-884
[10]   Core - shell upconversion nanoparticle - semiconductor heterostructures for photodynamic therapy [J].
Dou, Qing Qing ;
Rengaramchandran, Adith ;
Selvan, Subramanian Tamil ;
Paulmurugan, Ramasamy ;
Zhang, Yong .
SCIENTIFIC REPORTS, 2015, 5