Etiology and pathogenesis of multiple sclerosis

被引：39
|
作者：
Sorensen, TL
Ransohoff, RM
机构：
[1] Cleveland Clin Fdn, Lerner Res Inst, Dept Neurosci NC30, Cleveland, OH 44195 USA
[2] Cleveland Clin Fdn, Mellen Ctr Multiple Sclerosis Treatment & Res, Cleveland, OH 44195 USA
[3] Univ Copenhagen, Glostrup Hosp, Dept Neurol, DK-2600 Glostrup, Denmark
来源：
SEMINARS IN NEUROLOGY | 1998年 / 18卷 / 03期
关键词：
multiple sclerosis; pathogenesis;
D O I：
10.1055/s-2008-1040879
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The cause of multiple sclerosis (MS) remains unknown despite decades of intense research, The major research disciplines that have been brought to bear on this question include genetics, epidemiology, neuropathology, immunology, and virology, Recent advances in the understanding of the inflammatory characteristics of the MS lesion may herald the development of specific and effective treatments. The goal of this research is to improve our management of a disease that remains the major cause of neurologic disability among young adults in North America and Europe.
引用
收藏
页码：287 / 294
页数：8
相关论文
共 50 条
  • [1] Infection and the etiology and pathogenesis of multiple sclerosis
    Steiner, Israel
    Nisipianu, Puiu
    Wirguin, Itzhak
    CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2001, 1 (03) : 271 - 276
  • [2] Infection and the etiology and pathogenesis of multiple sclerosis
    Israel Steiner
    Puiu Nisipianu
    Itzhak Wirguin
    Current Neurology and Neuroscience Reports, 2001, 1 : 271 - 276
  • [3] Pathogenesis of multiple sclerosis
    Rejdak, Konrad
    AKTUALNOSCI NEUROLOGICZNE, 2009, 9 (02): : 86 - 90
  • [4] Carbohydrate and lipid metabolism in multiple sclerosis: Clinical implications for etiology, pathogenesis, diagnosis, prognosis, and therapy
    Pashaei, Somayeh
    Mohammadi, Pantea
    Yarani, Reza
    Haghgoo, Seyyed Mortaza
    Aleagha, Mohammad Sajad Emami
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021, 712
  • [5] Molecular pathogenesis of multiple sclerosis
    Bar-Or, A
    Oliveira, EML
    Anderson, DE
    Hafler, DA
    JOURNAL OF NEUROIMMUNOLOGY, 1999, 100 (1-2) : 252 - 259
  • [6] Pathogenesis of Pediatric Multiple Sclerosis
    Vargas-Lowy, David
    Chitnis, Tanuja
    JOURNAL OF CHILD NEUROLOGY, 2012, 27 (11) : 1394 - 1407
  • [7] Multiple Sclerosis: Pathogenesis and Treatment
    Loma, Ingrid
    Heyman, Rock
    CURRENT NEUROPHARMACOLOGY, 2011, 9 (03) : 409 - 416
  • [8] The pathogenesis of multiple sclerosis: a commentary
    Poser, CM
    CLINICAL NEUROLOGY AND NEUROSURGERY, 2000, 102 (04) : 191 - 194
  • [9] MicroRNAs associated with the pathogenesis of multiple sclerosis
    Huang, Qingrong
    Xiao, Bo
    Ma, Xinting
    Qu, Mingjuan
    Li, Yanmin
    Nagarkatti, Prakash
    Nagarkatti, Mitzi
    Zhou, Juhua
    JOURNAL OF NEUROIMMUNOLOGY, 2016, 295 : 148 - 161
  • [10] The pathogenesis and basis for treatment in multiple sclerosis
    Compston, A
    CLINICAL NEUROLOGY AND NEUROSURGERY, 2004, 106 (03) : 246 - 248
12345