The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality

被引:519
作者
Ilie, Petre Cristian [1 ]
Stefanescu, Simina [2 ]
Smith, Lee [3 ]
机构
[1] Queen Elizabeth Hosp Fdn Trust, Res & Innovat Dept, Kings Lynn, England
[2] Univ East Anglia, Norwich, Norfolk, England
[3] Anglia Ruskin Univ, Cambridge Ctr Sport & Exercise Sci, Cambridge, England
关键词
COVID-19; SARS-CoV2; Vitamin D; Cholecalciferol; Calcitriol; INFLUENZA; WOMEN;
D O I
10.1007/s40520-020-01570-8
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
WHO declared SARS-CoV-2 a global pandemic. The present aim was to propose an hypothesis that there is a potential association between mean levels of vitamin D in various countries with cases and mortality caused by COVID-19. The mean levels of vitamin D for 20 European countries and morbidity and mortality caused by COVID-19 were acquired. Negative correlations between mean levels of vitamin D (average 56 mmol/L, STDEV 10.61) in each country and the number of COVID-19 cases/1 M (mean 295.95, STDEV 298.7, and mortality/1 M (mean 5.96, STDEV 15.13) were observed. Vitamin D levels are severely low in the aging population especially in Spain, Italy and Switzerland. This is also the most vulnerable group of the population in relation to COVID-19. It should be advisable to perform dedicated studies about vitamin D levels in COVID-19 patients with different degrees of disease severity.
引用
收藏
页码:1195 / 1198
页数:4
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