68Ga-FAPI PET/CT Distinguishes the Reactive Lymph Nodes From Tumor Metastatic Lymph Nodes in a Patient With Nasopharyngeal Carcinoma

被引：18

作者：

Shang, Qihang ^{[1
,2
]}

Zhao, Long ^{[1
,2
]}

Pang, Yizhen ^{[1
,2
]}

Yu, Yifeng ^{[3
]}

Chen, Haojun ^{[1
,2
]}

机构：

[1] Xiamen Univ, Dept Nucl Med, Xiamen Canc Ctr, Affiliated Hosp 1, 55 Zhenhai Rd, Xiamen 361003, Peoples R China

[2] Xiamen Univ, Minnan PET Ctr, Xiamen Canc Ctr, Affiliated Hosp 1, 55 Zhenhai Rd, Xiamen 361003, Peoples R China

[3] Xiamen Univ, Dept Radiat Oncol, Xiamen Canc Ctr, Affiliated Hosp 1, Xiamen, Peoples R China

来源：

CLINICAL NUCLEAR MEDICINE | 2022年 / 47卷 / 04期

基金：

中国国家自然科学基金;

关键词：

F-18-FDG; Ga-68-FAPI; PET/CT; nasopharyngeal carcinoma; lymph node staging;

D O I：

10.1097/RLU.0000000000003939

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Accurate clinical staging is crucial for managing nasopharyngeal carcinoma (NPC). However, false-positive finding of cervical lymph nodes in 18F-FDG PET/CT and MRI may lead to unnecessary chemotherapy for NPC. In this case, we report a patient with NPC who was incorrectly diagnosed with bilateral cervical lymph node metastases by both 18F-FDG PET/CT and MRI. Subsequent pathology results showed proliferating lymphoid cells with no signs of tumor metastasis. Interestingly, no abnormal 68Ga-FAPI uptake was observed in the nonmetastatic reactive lymph nodes. Therefore, 68Ga-FAPI PET/CT may be useful for assessment of pretreatment lymph node status in NPC. © Wolters Kluwer Health, Inc. All rights reserved.

引用

页码：367 / 368

页数：2

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