Role of cytokine polymorphisms in the risk of distal gastric cancer development

被引:28
作者
Perez, GIP
Garza-Gonzalez, E
Portal, C
Olivares, AZ
机构
[1] NYU, Sch Med, Dept Med & Microbiol, New York, NY USA
[2] NYU, Sch Med, Dept Microbiol, New York, NY USA
[3] NYU, Sch Med, Dept Med, New York, NY USA
[4] Univ Autonoma Nuevo Leon, Fac Med, Dept Microbiol, Nuevo Leon, Mexico
关键词
D O I
10.1158/1055-9965.EPI-04-0889
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We review the current information concerning the role of cytokine polymorphisms and the risk of develop distal gastric cancer in different populations. We have included populations colonized with Helicobacter pylori as well as populations without colonization. We found that the study of polymorphisms alone seems insufficient to assess gastric cancer risk and it is necessary to examine environmental factors in different ethnic groups and geographic areas along with the study of H. pylori strains to define better the risk factors associated with distal gastric cancer.
引用
收藏
页码:1869 / 1873
页数:5
相关论文
共 36 条
[1]   Interleukin 1β and tumour necrosis factor α Inhibit acid secretion in cultured rabbit parietal cells by multiple pathways [J].
Beales, ILP ;
Calam, J .
GUT, 1998, 42 (02) :227-234
[2]   Cytokine gene polymorphism in human disease: on-line databases, Supplement 1 [J].
Bidwell, J ;
Keen, L ;
Gallagher, G ;
Kimberly, R ;
Huizinga, T ;
McDermott, MF ;
Oksenberg, J ;
McNicholl, J ;
Pociot, F ;
Hardt, C ;
D'Alfonso, S .
GENES AND IMMUNITY, 2001, 2 (02) :61-70
[3]  
BLASER MJ, 1995, CANCER RES, V55, P2111
[4]   Risks of interleukin-1 genetic polymorphisms and Helicobacter pylori infection in the development of gastric cancer [J].
Chen, A ;
Li, CN ;
Hsu, PI ;
Lai, KH ;
Tseng, HH ;
Hsu, PN ;
Lo, GH ;
Lo, CC ;
Lin, CK ;
Hwang, IR ;
Yamaoka, Y ;
Chen, HC .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2004, 20 (02) :203-211
[5]   Helicobacter pylori virulence and genetic geography [J].
Covacci, A ;
Telford, JL ;
Del Giudice, G ;
Parsonnet, J ;
Rappuoli, R .
SCIENCE, 1999, 284 (5418) :1328-1333
[6]   The importance of interleukin 1β in Helicobacter pylori associated disease [J].
El-Omar, EM .
GUT, 2001, 48 (06) :743-747
[7]   Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms [J].
El-Omar, EM ;
Rabkin, CS ;
Gammon, MD ;
Vaughan, TL ;
Risch, HA ;
Schoenberg, JB ;
Stanford, JL ;
Mayne, ST ;
Goedert, J ;
Blot, WJ ;
Fraumeni, JF ;
Chow, WH .
GASTROENTEROLOGY, 2003, 124 (05) :1193-1201
[8]   Interleukin-1 polymorphisms associated with increased risk of gastric cancer [J].
El-Omar, EM ;
Carrington, M ;
Chow, WH ;
McColl, KEL ;
Bream, JH ;
Young, HA ;
Herrera, J ;
Lissowska, J ;
Yuan, CC ;
Rothman, N ;
Lanyon, G ;
Martin, M ;
Fraumeni, JF ;
Rabkin, CS .
NATURE, 2000, 404 (6776) :398-402
[9]  
Figueiredo C, 2002, J NATL CANCER I, V94, P1680, DOI 10.1093/jnci/94.22.1680
[10]  
Forones NM, 2001, HEPATO-GASTROENTEROL, V48, P1199