Lower standing systolic blood pressure as a predictor of falls in the elderly: A community-based prospective study

被引:53
作者
Kario, K
Tobin, JN
Wolfson, LI
Whipple, R
Derby, CA
Singh, D
Marantz, PR
Wassertheil-Smoller, S
机构
[1] Clin Directors Network Inc, New York, NY 10018 USA
[2] Mt Sinai Sch Med, Zena & Michael A Wiener Cardiovasc Ctr, Bronx, NY USA
[3] Yeshiva Univ Albert Einstein Coll Med, Dept Epidemiol & Social Med, Bronx, NY 10461 USA
[4] Yeshiva Univ Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10461 USA
[5] Univ Connecticut, Ctr Hlth, Dept Neurol, Farmington, CT USA
关键词
D O I
10.1016/S0735-1097(01)01327-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives We investigated prospectively the relationships among falls, physical balance, and standing and supine blood pressure (BP) in elderly persons. Background Falls occur often and adversely affect the activities of daily living in the elderly; however, their relationship to BP has not been clarified thoroughly. Methods A total of 266 community-dwelling elderly persons age 65 years or over (123 men and 143 women, mean age of 76 years) were selected from among residents of Coop City, Bronx, New York. Balance was evaluated at baseline using computerized dynamic posturography (DPG). During a one-pear follow-up, we collected information on subsequent Falls on a monthly basis by postcard and telephone follow-up. Results One or more falls occurred in 60 subjects (22%) during the one-year follow-up. Women fell more frequently than men (28% vs. 16%, p < 0.03), and fallers were younger than nonfallers. Fallers (n = 60) had lower systolic BP (SBP) levels when compared with nonfallers (n = 200) (128 <plus/minus> 17 vs. 137 + 22 mm Hg for standing, p < 0.006; 137 <plus/minus> 16 vs. 144 +/- 22 mm Hg for lying, p < 0.02), whereas diastolic BP was not related to falls. Falls occurred 2.8 rimes more often in the lower BP subgroup (<140 mm Hg for standing SEP) than in the higher BP subgroup (greater than or equal to 140 mm Hg, p < 0.0003), and gender-related differences were observed (p = 0.006): 3.4 times for women (p < 0.0001) versus 1.9 times for men (p = 0.30). Loss of balance, as detected by DPG, did not predict future falls and was also not associated with baseline BP levels. Multiple logistic regression analysis demonstrated that female gender (relative risk [RR] = 2.1, p = 0.02), history of falls (RR = 2.5, p = 9.008) and lower standing SEP level(RR = 0.78 for 10 mm Hg increase, p = 0.005) were independent predictors of falls during one year of follow-up. Conclusions Lower standing SEP, even within normotensive ranges, was an independent predictor of falls in the community-dwelling elderly. Elderly women with a history of falls and with lower SEP levels should have more attention paid to the prevention of falls and related accidents. (J Am Coll Cardiol 2001;38:246-52) (C) 2001 by the American College of Cardiology.
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页码:246 / 252
页数:7
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