Pediatric Behcet disease: Update in diagnosis and management

被引:3
作者
Burns, Emily [1 ]
Cooper, Elizabeth [2 ]
Peterson, Rosemary [3 ]
Diaz, Lucia Z. [3 ,4 ]
机构
[1] Baylor Coll Med, Houston, TX 77030 USA
[2] UT Austin, Dell Med Sch, Div Dermatol, Dept Internal Med, Austin, TX 78712 USA
[3] UT Austin, Dell Med Sch, Div Pediat Rheumatol, Dept Pediat, Austin, TX 78712 USA
[4] UT Austin, Dell Med Sch, Div Pediat Dermatol, Dept Pediat, Austin, TX 78712 USA
关键词
Behcet disease; corticosteroid; inflammatory disorders; mucous membrane disorders; skin signs of systemic disease; GENOME-WIDE ASSOCIATION; DOUBLE-BLIND; CLINICAL CHARACTERISTICS; FAMILIAL AGGREGATION; SUSCEPTIBILITY LOCI; APHTHOUS ULCERS; PLACEBO; TRIAL; LESIONS; COLCHICINE;
D O I
10.1111/pde.14859
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Behcet disease is a multisystem inflammatory disease and variable vessel vasculitis involving primarily the oral and genital mucosa, skin, and eyes. Diagnosis is challenging due to the lack of a specific diagnostic test and overlap with other autoinflammatory diseases. Treatment of pediatric Behcet disease aims to reduce inflammation and prevent future flares. The goal of this review is to provide guidance on the diagnostic workup and multidisciplinary approach of pediatric Behcet disease and review evidence-based treatment strategies for patients with refractory mucocutaneous manifestations.
引用
收藏
页码:173 / 181
页数:9
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