Micrographia induced by pallidal DBS for segmental dystonia: a subtle sign of hypokinesia?

被引：43

作者：

Blahak, Christian ^{[1
]}

Capelle, Hans-Holger ^{[2
]}

Baezner, Hansjoerg ^{[1
]}

Kinfe, Thomas M. ^{[2
]}

Hennerici, Michael G. ^{[1
]}

Krauss, Joachim K. ^{[2
]}

机构：

[1] Heidelberg Univ, Univ Med Mannheim UMM, Dept Neurol, D-68167 Mannheim, Germany

[2] MHH, Hannover Med Sch, Dept Neurosurg, Hannover, Germany

来源：

JOURNAL OF NEURAL TRANSMISSION | 2011年 / 118卷 / 04期

关键词：

Dystonia; Deep brain stimulation; Globus pallidus internus; Micrographia; Hypokinesia; DEEP-BRAIN-STIMULATION; GLOBUS-PALLIDUS; PARKINSONS-DISEASE; INFARCTION; INTERNUS; LESIONS;

D O I：

10.1007/s00702-010-0544-y

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Recently parkinsonism has been reported as a rare side effect of globus pallidus internus (GPi) deep brain stimulation (DBS) for dystonia. In the present systematic prospective study in 11 patients with segmental dystonia not affecting distal arm function, we could demonstrate significant changes in handwriting characterized by mild micrographia following GPi-DBS. We propose that this finding reflects GPi-DBS-induced disturbances of basal ganglia function in terms of a mild hypokinetic syndrome, as a result of outflow alterations in pallido-thalamo-cortical pathways.

引用

页码：549 / 553

页数：5

共 25 条

[1]

[Anonymous], [No title captured]

[2] Pallidal stimulation for Parkinson's disease - Two targets? [J].

Bejjani, B ;

Damier, P ;

Arnulf, I ;

Bonnet, AM ;

Vidailhet, M ;

Dormont, D ;

Pidoux, B ;

Cornu, P ;

Marsault, C ;

Agid, Y .

NEUROLOGY, 1997, 49 (06) :1564-1569

[3] Induction of Bradykinesia with Pallidal Deep Brain Stimulation in Patients with Cranial-Cervical Dystonia [J].

Berman, Brian D. ;

Starr, Philip A. ;

Marks, William J., Jr. ;

Ostrem, Jill L. .

STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 2009, 87 (01) :37-44

[4] Health-related quality of life in segmental dystonia is improved by bilateral pallidal stimulation [J].

Blahak, C. ;

Woehrle, J. C. ;

Capelle, H. H. ;

Baezner, H. ;

Grips, E. ;

Weigel, R. ;

Kekelia, K. ;

Krauss, J. K. .

JOURNAL OF NEUROLOGY, 2008, 255 (02) :178-182

[5] A case of stroke induced micrographia [J].

Capone, F. ;

Pilato, F. ;

Profice, P. ;

Pravata, E. ;

Di Lazzaro, V. .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2009, 80 (12) :1356-1356

[6] MICROGRAPHIA IN PARKINSONS-DISEASE [J].

CONTRERASVIDAL, JL ;

TEULINGS, HL ;

STELMACH, GE .

NEUROREPORT, 1995, 6 (15) :2089-2092

[7] Micrographia secondary to lenticular lesions [J].

Derkinderen, P ;

Dupont, S ;

Vidal, JS ;

Chedru, F ;

Vidailhet, M .

MOVEMENT DISORDERS, 2002, 17 (04) :835-837

[8] Efficient internal pallidal stimulation in Gilles de la Tourette syndrome: A case report [J].

Diederich, NJ ;

Kalteis, K ;

Stamenkovic, M ;

Pieri, V ;

Alesch, F .

MOVEMENT DISORDERS, 2005, 20 (11) :1496-1499

[9] Acute deep-brain stimulation of the internal and external globus pallidus in primary dystonia [J].

Houeto, Jean-Luc ;

Yelnik, Jerome ;

Bardinet, Eric ;

Vercueil, Laurent ;

Krystkowiak, Pierre ;

Mesnage, Valerie ;

Lagrange, Christelle ;

Dormont, Didier ;

Le Bas, Jean-Francois ;

Pruvo, Jean-Pierre ;

du Moncel, Sophie Tezenas ;

Pollak, Pierre ;

Agid, Yves ;

Destee, Alain ;

Vidailhet, Marie .

ARCHIVES OF NEUROLOGY, 2007, 64 (09) :1281-1286

[10] Atypical micrographia associated with corticostriatal white matter lesions in systemic lupus erythematosus [J].

Ishihara, T. ;

Ozawa, T. ;

Otsuki, M. ;

Shimbo, J. ;

Tanaka, K. ;

Nishizawa, M. .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2006, 77 (08) :993-994

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