Biocompatibility improvement of polytetrafluoroethylene by ion implantation

被引：11

作者：

Kwon, Ho-Je ^{[1
]}

Jung, Chan-Hee ^{[1
]}

Kim, Dong-Ki ^{[1
]}

Lim, Youn-Mook ^{[1
]}

Kim, Hae-Kyoung ^{[1
]}

Nho, Young-Chang ^{[1
]}

Choi, Jae-Hak ^{[1
]}

机构：

[1] Korea Atom Energy Res Inst, Adv Radiat Technol Inst, Jeongeup 580185, South Korea

来源：

JOURNAL OF THE KOREAN PHYSICAL SOCIETY | 2008年 / 52卷 / 03期

关键词：

polytetrafluoroethylene; cell adhesion; ion implantation; surface modification;

D O I：

10.3938/jkps.52.819

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

A simple ion implantation process was successfully used for cell patterning. Polytetrafluoroethylene (PTFE) was implanted by 150 keV Ne+ ions with an ion fluence varying from 1 x 10(14) to 1 x 10(17) ions/cm(2). The physiochemical characteristics of the implanted PTFE, such as surface morphology, surface chemical composition and wettability, were investigated by means of scanning electron microscopy (SEM), X-ray photoelectron spectrometer (XPS), and water contact angle measurement. The biocompatibility of selectively implanted PTFE was studied via an in-vitro attachment of HaCaT cells. The surface morphology of the implanted surface became rougher with increasing fluence. XPS results showed that hydrophilic groups were formed on the implanted surface after implantation. With increasing fluence, the water contact angle was found to decrease. HaCaT cells were found to preferentially adhere to and proliferate on the implanted regions of PTFE.

引用

页码：819 / 823

页数：5

共 24 条

[1] Cell adhesion on nanofibrous polytetrafluoroethylene (nPTFE) [J].

Ainslie, Kristy M. ;

Bachelder, Eric M. ;

Borkar, Sachin ;

Zahr, Alisar S. ;

Sen, Ayusman ;

Badding, John V. ;

Pishko, Michael V. .

LANGMUIR, 2007, 23 (02) :747-754

[2] Modification of expanded polytetrafluoroethylene surface with low-energy nitrogen-ion-beam irradiation [J].

Choi, Yoon Jeong ;

Kim, Mi-Sook ;

Noh, Insup .

JOURNAL OF THE KOREAN PHYSICAL SOCIETY, 2007, 50 (05) :1579-1583

[3] Surface modification of a polytetrafluoroethylene film with cyclotron ion beams and its evaluation [J].

Choi, Yoon Jeong ;

Kim, Mi Sook ;

Noh, Insup .

SURFACE & COATINGS TECHNOLOGY, 2007, 201 (9-11) :5724-5728

[4] Formation of nanopore membranes and nanowires by high energy ion irradiation of polymer foils [J].

Ensinger, W. .

SURFACE & COATINGS TECHNOLOGY, 2007, 201 (19-20) :8442-8447

[5] Surface modification of polymeric materials by plasma immersion ion implantation [J].

Fu, RKY ;

Cheung, ITL ;

Mei, YF ;

Shek, CH ;

Siu, GG ;

Chu, PK ;

Yang, WM ;

Leng, YX ;

Huang, YX ;

Tian, XB ;

Yang, SQ .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 2005, 237 (1-2) :417-421

[6] Photochemical surface modification of PET by excimer UV lamp irradiation [J].

Gao, SL ;

Hässler, R ;

Mäder, E ;

Bahners, T ;

Opwis, K ;

Schollmeyer, E .

APPLIED PHYSICS B-LASERS AND OPTICS, 2005, 81 (05) :681-690

[7] Ion beam induced enhanced adhesion of Au films deposited on polytetrafluoroethylene [J].

Guzman, L ;

Man, BY ;

Miotello, A ;

Adami, M ;

Ossi, PM .

THIN SOLID FILMS, 2002, 420 :565-570

[8] Oxygen plasma treatment to restrain nickel out-diffusion from porous nickel titanium orthopedic materials [J].

Ho, J. P. Y. ;

Wu, S. L. ;

Poon, R. W. Y. ;

Chung, C. Y. ;

Tjong, S. C. ;

Chu, P. K. ;

Yeung, K. W. K. ;

Lu, W. W. ;

Cheung, K. M. C. ;

Luk, K. D. K. .

SURFACE & COATINGS TECHNOLOGY, 2007, 201 (9-11) :4893-4896

[9] Ultra-hydrophobic fluorine polymer by Ar-ion bombardment [J].

Inoue, Y ;

Yoshimura, Y ;

Ikeda, Y ;

Kohno, A .

COLLOIDS AND SURFACES B-BIOINTERFACES, 2000, 19 (03) :257-261

[10]

Ishikawa J, 2006, J KOREAN PHYS SOC, V48, P703

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