A decade of caspases

被引：942
作者：
Degterev, A [1 ]
Boyce, M [1 ]
Yuan, JY [1 ]
机构：
[1] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA
来源：
ONCOGENE | 2003年 / 22卷 / 53期
关键词：
caspase; apoptosis; protease;
D O I：
10.1038/sj.onc.1207107
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Caspases are a family of cysteine proteases that play important roles in regulating apoptosis. A decade of research has generated a wealth of information on the signal transduction pathways mediated by caspases, the distinct functions of individual caspases and the mechanisms by which caspases mediate apoptosis and a variety of physiological and pathological processes.
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收藏
页码：8543 / 8567
页数：25
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