First-in-human study of PF-00299804, a small molecule irreversible panHER inhibitor in patients with advanced cancer: Update on safety and pharmacokinetics and initial report on pharmacodynamic responses and clinical benefit

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作者
Camidge, D. R. [1 ]
Britten, C. D. [2 ]
Schellens, J. H. M. [3 ]
Guo, F. [4 ]
Milham, R. [4 ]
Eckhardt, S. G. [1 ]
Wong, S. G. [2 ]
Boss, D. S. [3 ]
Lucca, J. [5 ]
Jannes, P. A. [5 ]
机构
[1] Univ Colorado, Denver, CO USA
[2] Univ Calif Los Angeles, Los Angeles, CA 90024 USA
[3] Netherlands Canc Inst, Amsterdam, Netherlands
[4] Pfizer Global Res & Dev, New London, CT USA
[5] Dana Farber Canc Inst, Boston, MA USA
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R73 [肿瘤学];
学科分类号
100214 ;
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页码:3505S / 3505S
页数:1
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