COVID-19 outcomes in patients with antiphospholipid syndrome: a retrospective cohort study

被引:4
作者
Erden, A. [1 ,2 ]
Karakas, O. [1 ,2 ]
Armagan, B. [1 ,2 ]
Guven, S. C. [1 ,2 ]
Ozdemir, B. [1 ,2 ]
Atalar, E. [1 ,2 ]
Apaydin, H. [1 ,2 ]
Usul, E. [1 ,3 ]
Ates, I [1 ,4 ]
Omma, A. [1 ,2 ]
Kucuksahin, O. [1 ,5 ]
机构
[1] Ankara Sehir Hastanesi, MH6 Onkol Binasi, Romatol Bolumu, TR-06800 Ankara, Turkey
[2] Minist Hlth, Clin Rheumatol, Ankara City Hosp, Ankara, Turkey
[3] Sincan Dr Nafiz Korez State Hosp, Clin Emergency Med, Ankara, Turkey
[4] Univ Hlth Sci, Minist Hlth, Sch Med, Dept Internal Med,Ankara City Hosp, Ankara, Turkey
[5] Ankara Yildirim Bayezit Univ, Sch Med, Dept Internal Med, Div Rheumatol, Ankara, Turkey
关键词
antiphospholipid syndrome; COVID-19; outcome; thrombosis; mortality; INTERNATIONAL CONSENSUS STATEMENT; CLASSIFICATION CRITERIA; MECHANISMS;
D O I
10.4149/BLL_2022_018
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND: Aim of this study is to investigate COVID-19 outcomes in patients with antiphospholipid syndrome (APS). METHODS: A retrospective cohort was formed from APS patients. Patients were screened for a record of positive SARS-CoV 2 PCR. In PCR-positive patients, clinical data and information regarding COVID-19 outcomes were collected from medical records. RESULTS: A positive PCR test was detected in 9/53 APS patients, while 66.7 %, 33.3 % and 11.1 % of APS patients with COVID-19 were under hydroxychloroquine, LMWH or warfarin, and acetylsalicylic acid, respectively. There were 3/9 patients found to be hospitalized and one died. No new thrombotic event was reported in any of the patients during COVID-19 infection. CONCLUSION: Baseline use of hydroxychloroquine, antiaggregants and anticoagulants may be associated with an absence of new thrombotic event (Tab. 2, Ref. 33). Text in PDF www.elis.sk
引用
收藏
页码:120 / 124
页数:5
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