Isolation and characterization of phenolic compounds from Rhodiola imbricata, a Trans-Himalayan food crop having antioxidant and anticancer potential

被引：19

作者：

Choudhary, Alka ^{[1
]}

Kumar, Raj ^{[2
]}

Srivastava, Ravi Bihari ^{[2
]}

Surapaneni, Sunil Kumar ^{[3
]}

Tikoo, Kulbhushan ^{[3
]}

Singh, Inder Pal ^{[1
]}

机构：

[1] NIPER, Dept Nat Prod, Sas Nagar 160062, Punjab, India

[2] Def Inst High Altitude Res DRDO, Div Phytochem, Leh Ladakh 901205, J&K, India

[3] NIPER, Dept Pharmacol & Toxicol, Sas Nagar 160062, Punjab, India

来源：

JOURNAL OF FUNCTIONAL FOODS | 2015年 / 16卷

关键词：

Rhodiola imbricata; Crassulaceae; Phenolic glycosides; Antioxidant activity; Anticancer activity; AQUEOUS EXTRACT; GLYCOSIDES; CONSTITUENTS; FULGENS; NUCLEAR; ROOTS;

D O I：

10.1016/j.jff.2015.04.013

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

The root of Rhodiola imbricata, a Trans Himalayan food crop is known for its antioxidant and adaptogenic properties. Four new compounds (7, 11, 12 and 15) together with known phenolic glycosides (10, 13-14, 16-19) and other phenolics (1-6, 8-9) were isolated from the ethyl acetate extract of the roots of R. imbricata. The structures of isolated molecules were established by spectroscopic techniques (ESI-HRMS, 1D and 2D NMR) and chemical methods. The compounds were evaluated for their antioxidant (radical scavenging, MTT antioxidant, linoleic acid peroxidation and reducing power assay) and anticancer activities against A-549 and MCF-7 cancer cell lines. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：183 / 193

页数：11

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