Resveratrol in the Prevention and Treatment of Coronary Artery Disease

被引：35
作者：
Chu, Louis M. [2 ]
Lassaletta, Antonio D. [2 ]
Robich, Michael P. [3 ]
Sellke, Frank W. [1 ,2 ]
机构：
[1] Brown Univ, Alpert Med Sch, Div Cardiothorac Surg, Providence, RI 02903 USA
[2] Brown Univ, Warren Alpert Med Sch, Dept Surg, Div Cardiothorac Surg, Providence, RI 02903 USA
[3] Beth Israel Deaconess Med Ctr, Dept Surg, Boston, MA 02215 USA
来源：
CURRENT ATHEROSCLEROSIS REPORTS | 2011年 / 13卷 / 06期
关键词：
Resveratrol; Coronary artery disease; Atherosclerosis; Cholesterol; Metabolic syndrome; Ischemia-reperfusion; Chronic ischemia; Angiogenesis; Antioxidant; SMOOTH-MUSCLE-CELLS; ALCOHOL-CONSUMPTION; HEART-DISEASE; MODERATE ALCOHOL; RED WINE; RISK; MECHANISMS; MORTALITY; ATHEROSCLEROSIS; PROLIFERATION;
D O I：
10.1007/s11883-011-0202-3
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Resveratrol is a polyphenolic compound found in red wine that is believed to be responsible for its beneficial cardiovascular effects. Extensive research in the past several decades has identified multiple mechanisms by which resveratrol modifies the cardiovascular risk factors that lead to coronary artery disease, yet translation to the clinical arena has been unexpectedly slow. In this article, we review the existing evidence regarding the beneficial effects of resveratrol and briefly discuss its potential therapeutic applications.
引用
收藏
页码：439 / 446
页数：8
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