The synthesis of pennogenin 3-O-β-D-glucopyranosyl-(1 → 3)-[α-L-rhamnopyranosyl-(1 → 2)]-β-D-glucopyranoside

被引：6
|
作者：
Luo, Xin-Feng [1 ]
Lei, Fan [1 ]
He, Yi [1 ]
Pei, Shu-Chen [1 ]
Hai, Li [1 ]
Qian, Shan [2 ]
Wu, Yong [1 ]
机构：
[1] Sichuan Univ, W China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Educ Minist, Chengdu 610041, Peoples R China
[2] Xihua Univ, Bioengn Coll, Chengdu 610039, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2012年 / 14卷 / 04期
关键词：
pennogenin; alpha-L-rhamnopyranoside; beta-D-glucopyranoside; antitumor activity; synthesis; GRACILLIN; SAPONINS; GLYCOSYL;
D O I：
10.1080/10286020.2011.653348
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Pennogenin 3-O-beta-D-glucopyranosyl-(1 -> 3)-[alpha-L-rhamnopyranosyl-(1 -> 2)]-beta-D-glucopyranoside, a monodesmosidic saponin isolated from Paris polyphylla Smith var. yunnanensis with promised antitumor activities, was firstly synthesized from glucoside thiol via nine steps and with 27% overall yield.
引用
收藏
页码：314 / 321
页数：8
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