Feature selection based on sensitivity analysis of fuzzy ISODATA

被引:24
|
作者
Liu, Quanjin [1 ,2 ]
Zhao, Zhimin [1 ]
Li, Ying-Xin [3 ]
Li, Yuanyuan [1 ]
机构
[1] Nanjing Univ Aeronaut & Astronaut, Coll Sci, Nanjing 210016, Jiangsu, Peoples R China
[2] AnQing Normal Coll, Sch Phys & Elect Engn, Anqing 246011, Peoples R China
[3] Beijing Jingwei Text Machinery New Technol Co Ltd, Inst Machine Vis & Machine Intelligence, Beijing 100176, Peoples R China
基金
中国国家自然科学基金; 高等学校博士学科点专项科研基金;
关键词
Feature selection; Fuzzy ISODATA; Sensitivity analysis; Microarray; Classification; Clustering; SUPPORT VECTOR MACHINES; CANCER-DIAGNOSIS; MICROARRAY DATA; GENE SELECTION; CLASSIFICATION; ALGORITHM; PERFORMANCE; PREDICTION; WRAPPERS; TUMOR;
D O I
10.1016/j.neucom.2012.01.005
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
A feature selection method based on sensitivity analysis and the fuzzy Interactive Self-Organizing Data Algorithm (ISODATA) is proposed for selecting features from high dimensional gene expression data sets. First, feature sensitivities for discriminating classes are calculated on the basis of the fuzzy ISODATA method. Then, candidate feature subsets are generated according to feature sensitivities with the recursive feature elimination procedure. Finally, the obtained optimal feature subsets are evaluated using both supervised and unsupervised methods to validate their abilities for separating different categories. The proposed method is applied to five microarray datasets, and the experimental results indicate its effectiveness. (c) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:29 / 37
页数:9
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