Solution and chips arrays in protein profiling

被引：67
作者：
Zhou, HH [1 ]
Roy, S [1 ]
Schulman, H [1 ]
Natan, MJ [1 ]
机构：
[1] SurroMed, Mt View, CA 94043 USA
来源：
TRENDS IN BIOTECHNOLOGY | 2001年 / 19卷 / 10期
关键词：
D O I：
10.1016/S0167-7799(01)01798-X
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The industrialization of proteomics demands reproducible, robust and high-throughput profiling technologies, that current two-dimensional gel electrophoresis cannot achieve. New technologies in protein arrays, either on chips, or with self-encoded elements in: solution, hold much promise for interrogating the diverse and immense proteome.
引用
收藏
页码：S34 / S39
页数：6
相关论文
共 33 条
[1]   Protein microchips: Use for immunoassay and enzymatic reactions [J].
Arenkov, P ;
Kukhtin, A ;
Gemmell, A ;
Voloshchuk, S ;
Chupeeva, V ;
Mirzabekov, A .
ANALYTICAL BIOCHEMISTRY, 2000, 278 (02) :123-131
[2]   Toward larger chemical libraries: Encoding with fluorescent colloids in combinatorial chemistry [J].
Battersby, BJ ;
Bryant, D ;
Meutermans, W ;
Matthews, D ;
Smythe, ML ;
Trau, M .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (09) :2138-2139
[3]   Semiconductor nanocrystals as fluorescent biological labels [J].
Bruchez, M ;
Moronne, M ;
Gin, P ;
Weiss, S ;
Alivisatos, AP .
SCIENCE, 1998, 281 (5385) :2013-2016
[4]  
BURLINGAME AL, 2000, MASS SPECTROMETRY BI
[5]   Large-scale functional analysis using peptide or protein arrays [J].
Emili, AQ ;
Cagney, G .
NATURE BIOTECHNOLOGY, 2000, 18 (04) :393-397
[6]  
Fulton RJ, 1997, CLIN CHEM, V43, P1749
[7]   Protein biochips for differential profiling [J].
Fung, ET ;
Thulasiraman, V ;
Weinberger, SR ;
Dalmasso, EA .
CURRENT OPINION IN BIOTECHNOLOGY, 2001, 12 (01) :65-69
[8]  
Gaber BP, 1999, CHEMTECH, V29, P20
[9]   Quantitative analysis of complex protein mixtures using isotope-coded affinity tags [J].
Gygi, SP ;
Rist, B ;
Gerber, SA ;
Turecek, F ;
Gelb, MH ;
Aebersold, R .
NATURE BIOTECHNOLOGY, 1999, 17 (10) :994-999
[10]  
HAAB BB, 2001, GENOME BIOL, V2
1234