DNA based biosensors

被引:103
作者
Zhai, JH
Cui, H
Yang, RF
机构
[1] Inst. of Microbiol. and Epidemiology, Beijing 100071, 20 Dongdajie, Fengtai District
关键词
DNA biosensor; biosensors; nucleic acid hybridization;
D O I
10.1016/S0734-9750(97)00003-7
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Compared to advances in enzyme sensors, immunosensors, and microbial biosensors, relatively little work exists on DNA based biosensors. Here we review the DNA based biosensors that rely on nucleic acid hybridization. Major types DNA biosensors-electrochemical, optical, acoustic, and piezoelectric-are introduced and compared. The specificity and response characteristics of DNA biosensors are discussed. Overall, a promising future is foreseen for the DNA based sensor technology. (C) 1997 Elsevier Science Inc.
引用
收藏
页码:43 / 58
页数:16
相关论文
共 57 条
[1]   THE DESIGN OF ENZYME SENSORS BASED ON THE ENZYME STRUCTURE [J].
ALVAREZICAZA, M ;
KALISZ, HM ;
HECHT, HJ ;
AUMANN, KD ;
SCHOMBURG, D ;
SCHMID, RD .
BIOSENSORS & BIOELECTRONICS, 1995, 10 (08) :735-742
[2]  
[Anonymous], 1991, BIOSENSORS
[3]   THE RESONANT MIRROR - A NOVEL OPTICAL SENSOR FOR DIRECT SENSING OF BIOMOLECULAR INTERACTIONS .2. APPLICATIONS [J].
BUCKLE, PE ;
DAVIES, RJ ;
KINNING, T ;
YEUNG, D ;
EDWARDS, PR ;
POLLARDKNIGHT, D ;
LOWE, CR .
BIOSENSORS & BIOELECTRONICS, 1993, 8 (7-8) :355-363
[5]   SURFACE ACOUSTIC-WAVE DEVICES AS CHEMICAL SENSORS IN LIQUIDS - EVIDENCE DISPUTING THE IMPORTANCE OF RAYLEIGH-WAVE PROPAGATION [J].
CALABRESE, GS ;
WOHLTJEN, H ;
ROY, MK .
ANALYTICAL CHEMISTRY, 1987, 59 (06) :833-837
[6]   DETECTION OF POLY(U) HYBRIDIZATION USING AZIDO MODIFIED POLY(A)-COATED PIEZOELECTRIC-CRYSTALS [J].
CAMPBELL, NF ;
EVANS, JA ;
FAWCETT, NC .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993, 196 (02) :858-863
[7]  
Chang R.K., 1982, Surface Enhanced Raman Scattering
[8]   DISRUPTION OF MICROBIAL-CELLS FOR INTRACELLULAR PRODUCTS [J].
CHISTI, Y ;
MOOYOUNG, M .
ENZYME AND MICROBIAL TECHNOLOGY, 1986, 8 (04) :194-204
[9]  
CHISTI Y, 1996, BIOTECHNOL ADV, V14, P437
[10]  
CLARK LC, 1962, ANN NY ACAD SCI, V102, P1742