Medical Marijuana for Digestive Disorders: High Time to Prescribe?

被引:43
作者
Gerich, Mark E. [1 ]
Isfort, Robert W. [1 ]
Brimhall, Bryan [2 ]
Siegel, Corey A. [3 ]
机构
[1] Univ Colorado, Div Gastroenterol & Hepatol, Aurora, CO 80045 USA
[2] Univ Colorado, Dept Med, Aurora, CO 80045 USA
[3] Dartmouth Hitchcock Med Ctr, Ctr Inflammatory Bowel Dis, Lebanon, NH 03766 USA
关键词
CHEMOTHERAPY-INDUCED NAUSEA; CANNABINOID RECEPTOR; THERAPEUTIC-USE; CANCER-PATIENTS; LIVER-DISEASES; CLINICAL-TRIAL; CALORIC-INTAKE; DOUBLE-BLIND; WEIGHT-LOSS; CASE SERIES;
D O I
10.1038/ajg.2014.245
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The use of recreational and medical marijuana is increasingly accepted by the general public in the United States. Along with growing interest in marijuana use has come an understanding of marijuana's effects on normal physiology and disease, primarily through elucidation of the human endocannabinoid system. Scientific inquiry into this system has indicated potential roles for marijuana in the modulation of gastrointestinal symptoms and disease. Some patients with gastrointestinal disorders already turn to marijuana for symptomatic relief, often without a clear understanding of the risks and benefits of marijuana for their condition. Unfortunately, that lack of understanding is shared by healthcare providers. Marijuana's federal legal status as a Schedule I controlled substance has limited clinical investigation of its effects. There are also potential legal ramifications for physicians who provide recommendations for marijuana for their patients. Despite these constraints, as an increasing number of patients consider marijuana as a potential therapy for their digestive disorders, health-care providers will be asked to discuss the issues surrounding medical marijuana with their patients.
引用
收藏
页码:208 / 214
页数:7
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