Trichilia glabra:: effect on the phagocytic activity and respiratory burst response of peritoneal macrophages

被引：6

作者：

Benencia, F ^{[1
]}

Courrèges, MC ^{[1
]}

Coulombié, FC ^{[1
]}

机构：

[1] Univ Buenos Aires, Fac Sci, Dept Biol Chem, Virol Lab, RA-1428 Buenos Aires, DF, Argentina

来源：

IMMUNOPHARMACOLOGY | 1999年 / 41卷 / 01期

关键词：

mice; Trichilia glabra; respiratory burst response; macrophages; immunomodulation;

D O I：

10.1016/S0162-3109(98)00054-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A diminution in the phagocytic capability and respiratory burst response of murine peritoneal macrophages was observed when these cells were treated 'in vitro' with Trichilia glabra leaf aqueous extract. The effect was not observed when non-specific phagocytosis was tested. The extract also inhibited binding of opsonized erythrocytes to macrophages, thus indicating that the observed antiphagocytic effect is possibly due to the failure of opsonized particles to bind to these cells. A low molecular weight fraction is responsible for the reported activities. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：45 / 53

页数：9

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