Levetiracetam in progressive myoclonic epilepsy - An exploratory study in 9 patients

被引：43
作者：
Crest, C
Dupont, S
Leguern, E
Adam, C
Baulac, M
机构：
[1] Hop La Pitie Salpetriere, Clin Neurol Paul Castaigne, Unite Epileptol, F-75651 Paris 13, France
[2] Hop La Pitie Salpetriere, INSERM, EMI Cortex & Epilepsie 0224, Paris, France
[3] Hop La Pitie Salpetriere, INSERM, U289, Neurogenet Lab,Dept Genet Cytogenet & Embryol, Paris, France
来源：
NEUROLOGY | 2004年 / 62卷 / 04期
关键词：
D O I：
10.1212/01.WNL.0000110193.78872.DD
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The authors conducted an open study of levetiracetam as add-on therapy in nine patients with well-defined progressive myoclonic epilepsies and refractory myoclonus. Myoclonus was evaluated semiquantitatively (territory, intensity, daily living activities). Five patients had improvement of their myoclonus score. Levetiracetam may benefit myoclonus in progressive myoclonic epilepsy.
引用
收藏
页码：640 / 643
页数：4
相关论文
共 9 条
  • [1] FAMILIAL PROGRESSIVE MYOCLONUS EPILEPSY - CLINICAL AND ELECTROPHYSIOLOGIC OBSERVATIONS
    ACHARYA, JN
    SATISHCHANDRA, P
    SHANKAR, SK
    [J]. EPILEPSIA, 1995, 36 (05) : 429 - 434
  • [2] Genton P, 2000, EPILEPTIC DISORD, V2, P209
  • [3] Suppression of post-hypoxic and post-encephalitic myoclonus with levetiracetam
    Genton, P
    Gelisse, P
    [J]. NEUROLOGY, 2001, 57 (06) : 1144 - 1145
  • [4] Genton P, 2000, EPILEPTIC DISORD, V2, P99
  • [5] Efficacy of levetiracetam in a patient with Unverricht-Lundborg progressive myoclonic epilepsy
    Kinrions, P
    Ibrahim, N
    Murphy, K
    Lehesjoki, AE
    Järvela, I
    Delanty, N
    [J]. NEUROLOGY, 2003, 60 (08) : 1394 - 1395
  • [6] Suppression of posthypoxic and postencephalitic myoclonus with levetiracetam
    Krauss, GL
    Bergin, A
    Kramer, RE
    Cho, YW
    Reich, SG
    [J]. NEUROLOGY, 2001, 56 (03) : 411 - 412
  • [7] Zonisamide for progressive myoclonus epilepsy: long-term observations in seven patients
    Kyllerman, M
    Ben-Menachem, E
    [J]. EPILEPSY RESEARCH, 1998, 29 (02) : 109 - 114
  • [8] Desynchronizing effect of levetiracetam on epileptiform responses in rat hippocampal slices
    Niespodziany, I
    Klitgaard, H
    Margineanu, DG
    [J]. NEUROREPORT, 2003, 14 (09) : 1273 - 1276
  • [9] Suppression of cortical myoclonus by levetiracetam
    Schauer, R
    Singer, M
    Saltuari, L
    Kofler, M
    [J]. MOVEMENT DISORDERS, 2002, 17 (02) : 411 - 415
1