A Fully Integrated CMOS Nanoscale Biosensor Microarray

被引:0
|
作者
Zhang, Lei [1 ]
He, Xiangqing [1 ]
Wang, Yan [1 ]
Yu, Zhiping [1 ]
机构
[1] Tsinghua Univ, Tsinghua Natl Lab Informat Sci & Technol, Inst Microelect, Beijing 100084, Peoples R China
关键词
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
This paper presents a fully integrated CMOS microarray for biosensor applications. A 64-pixel working electrode array with optimized reference and counter electrode structure is proposed to improve symmetry, and the feature sizes of electrodes have been scaled down to 600nm. The circuit utilizes the decoding scheme of memories to simplify the pixel design while shares potentiostat opamp and current amplifers, which allows the miniaturization of electrodes and enables large-scale integration of the microarray. The demo is fabricated in 0.18 mu m CMOS technology, and experimental results successfully demonstrated the biosensing detections on the nanoscale microarray. The circuit provides a current gain of 19.9dB, 3dB bandwidth of 15kHz, dynamic range of 141dB, sensing sensitivity of 37.6pA, and a driving capability of 0.46mA, respectively.
引用
收藏
页数:4
相关论文
共 50 条
  • [11] FinFETs for nanoscale CMOS digital integrated circuits
    King, TJ
    ICCAD-2005: INTERNATIONAL CONFERENCE ON COMPUTER AIDED DESIGN, DIGEST OF TECHNICAL PAPERS, 2005, : 207 - 210
  • [12] Nanoscale Biosensor with Integrated Temperature Controller for DNA Diagnostics
    Tsiniaikin, I. I.
    Presnova, G. V.
    Bozhev, I. V.
    Skorik, A. A.
    Rubtsova, M. Yu.
    Trifonov, A. S.
    Snigirev, O. V.
    Krupenin, V. A.
    Presnov, D. E.
    MOSCOW UNIVERSITY PHYSICS BULLETIN, 2023, 78 (02) : 214 - 220
  • [13] Nanoscale Biosensor with Integrated Temperature Controller for DNA Diagnostics
    I. I. Tsiniaikin
    G. V. Presnova
    I. V. Bozhev
    A. A. Skorik
    M. Yu. Rubtsova
    A. S. Trifonov
    O. V. Snigirev
    V. A. Krupenin
    D. E. Presnov
    Moscow University Physics Bulletin, 2023, 78 : 214 - 220
  • [14] A fully integrated CMOS sensor for optical tracking
    Massari, N
    Viarani, N
    Gonzo, L
    Gottardi, M
    Simoni, A
    SIXTH INTERNATIONAL CONFERENCE ON VIBRATION MEASUREMENTS BY LASER TECHNIQUES: ADVANCES AND APPLICATIONS, 2004, 5503 : 272 - 279
  • [15] Fully integrated 10 GHz CMOS VCO
    Do, MA
    Zhao, R
    Yeo, KS
    Ma, JG
    ELECTRONICS LETTERS, 2001, 37 (16) : 1021 - 1023
  • [16] Fully integrated CMOS UWB pulse generator
    Bachelet, Y.
    Bourdel, S.
    Gaubert, J.
    Bas, G.
    Chalopin, H.
    ELECTRONICS LETTERS, 2006, 42 (22) : 1277 - 1278
  • [17] CMOS fully digital integrated pressure sensors
    Chau, MT
    Dominguez, D
    Bonvalot, B
    Suski, J
    SENSORS AND ACTUATORS A-PHYSICAL, 1997, 60 (1-3) : 86 - 89
  • [18] A fully integrated CMOS sensor system for chronocoulometry
    Paulus, C
    Wieder, H
    Musewald, C
    Lossau, H
    Thewes, R
    PROCEEDINGS OF THE IEEE SENSORS 2003, VOLS 1 AND 2, 2003, : 1329 - 1332
  • [19] Fully integrated CMOS magnetic current monitor
    Univ of Pavia, Pavia, Italy
    Proc IEEE Int Symp Circuits Syst, (V-128-V-131):
  • [20] Advances in fully CMOS integrated photonic devices
    Michel, Jurgen
    Liu, J. F.
    Ahn, D. H.
    Sparacin, D.
    Sun, R.
    Hong, C. Y.
    Giziewicz, W. P.
    Beals, M.
    Kimerling, L. C.
    Kopa, A.
    Apsel, A. B.
    Rasras, M. S.
    Gill, D. M.
    Patel, S. S.
    Tu, K. Y.
    Chen, Y. K.
    White, A. E.
    Pomerene, A.
    Carothers, D.
    Grove, M. J.
    SILICON PHOTONICS II, 2007, 6477