Detection of Salmonella enterica, Subsp enterica Serovar Typhi in Dengue Virus Seropositive Samples

被引:0
作者
Younas, Saima [1 ]
Amin, Iram [2 ]
Shahid, Muhammad [2 ]
Fatima, Zareen [2 ]
Idreesi, Muhammad [1 ]
机构
[1] Univ Punjab, CAMB, Lahore, Pakistan
[2] Univ Punjab, Natl Ctr Excellence Mol Biol CEMB, Div Mol Virol, Lahore, Pakistan
关键词
Dengue Virus infection; Typhoid fever; Co-infection; S; typhi; FEVER; SURVEILLANCE;
D O I
暂无
中图分类号
Q95 [动物学];
学科分类号
071002 ;
摘要
Dengue virus infections and typhoid fever are among the endemic diseases in tropical and sub tropical regions of world. Bacteraemia with dengue co-infection is rare. Present study was designed to detect dengue virus RNA and then to test those samples for the detection of S typhi to check the co infection rate of these two infectious agents in Pakistani population. A total of 365 subjects were included in this study, out of which 224 (61.7%) were males and 141(38.2%) were females. The median age of patients was 40 +/- 32, percentage of dengue positive samples was found to be higher in age group 31y-40y and 41y-50y.75 % of total samples included in the study were positive for dengue virus RNA where as 24.6% were those in which dengue virus RNA was not detected. DENV-2 was found to be the most prevalent serotype while DENV-1, DENV-3 and DENV-4 were not detected in any of the sample. Of the 274 samples with DENV-2, only 4 samples were positive for S typhi. S. typhi was also detected in 3 patients who were negative for dengue virus PCR. The presence of S. typhi in dengue positive samples was further confirmed by sequencing PCR products.
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页码:1741 / 1746
页数:6
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