Pbx4, a new Pbx family member on mouse chromosome 8, is expressed during spermatogenesis

被引:60
作者
Wagner, K
Mincheva, A
Korn, B
Lichter, P
Pöpperl, H
机构
[1] Deutsch Krebsforschungszentrum, Abt Pathogenitatsmechanismen, D-69120 Heidelberg, Germany
[2] Deutsch Krebsforschungszentrum, Abt Org Komplexer Genome, D-69120 Heidelberg, Germany
[3] Deutsch Krebsforschungszentrum, Abt Mol Genomanalyse, D-69120 Heidelberg, Germany
关键词
Pbx4; PBX4; homeobox; spermatogenesis;
D O I
10.1016/S0925-4773(01)00349-5
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Members of the Pbx family are involved in a diverse range of developmental processes including axial patterning and organogenesis. Pbx Functions are in part mediated by the interaction of Pbx proteins with members of the Hox and Meis/Prep families. We have identified a fourth mammalian Pbx family member. Pbx4 in the mouse and PBX4 in humans are located on chromosome 8 and chromosome 19, respectively. Pbx4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:127 / 131
页数:5
相关论文
共 13 条
  • [1] BELLVE AR, 1993, METHOD ENZYMOL, V225, P84
  • [2] Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals
    Burglin, TR
    [J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (21) : 4173 - 4180
  • [3] XY body formation during rat spermatogenesis: an immunocytochemical study using antibodies against XY body-associated proteins
    Kralewski, M
    Benavente, R
    [J]. CHROMOSOMA, 1997, 106 (05) : 304 - 307
  • [4] A novel Mr 77,000 protein of the XY body of mammalian spermatocytes: its localization in normal animals and in Searle's translocation carriers
    Kralewski, M
    Novello, A
    Benavente, R
    [J]. CHROMOSOMA, 1997, 106 (03) : 160 - 167
  • [5] HIGH-RESOLUTION MAPPING OF HUMAN CHROMOSOME-11 BY INSITU HYBRIDIZATION WITH COSMID CLONES
    LICHTER, P
    TANG, CJC
    CALL, K
    HERMANSON, G
    EVANS, GA
    HOUSMAN, D
    WARD, DC
    [J]. SCIENCE, 1990, 247 (4938) : 64 - 69
  • [6] PBX2 AND PBX3, NEW HOMEOBOX GENES WITH EXTENSIVE HOMOLOGY TO THE HUMAN PROTOONCOGENE PBX1
    MONICA, K
    GALILI, N
    NOURSE, J
    SALTMAN, D
    CLEARY, ML
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (12) : 6149 - 6157
  • [7] CHROMOSOMAL TRANSLOCATION-T(1-19) RESULTS IN SYNTHESIS OF A HOMEOBOX FUSION MESSENGER-RNA THAT CODES FOR A POTENTIAL CHIMERIC TRANSCRIPTION FACTOR
    NOURSE, J
    MELLENTIN, JD
    GALILI, N
    WILKINSON, J
    STANBRIDGE, E
    SMITH, SD
    CLEARY, ML
    [J]. CELL, 1990, 60 (04) : 535 - 545
  • [8] CHROMOSOME BEHAVIOR DURING EARLY MEIOTIC PROPHASE OF MOUSE PRIMARY SPERMATOCYTES
    OUD, JL
    REUTLINGER, AHH
    [J]. CHROMOSOMA, 1981, 83 (03) : 395 - 407
  • [9] Iazarus is a novel pbx gene that globally mediates Hox gene function in zebrafish
    Pöpperl, H
    Rikhof, H
    Chang, H
    Haffter, P
    Kimmel, CB
    Moens, CB
    [J]. MOLECULAR CELL, 2000, 6 (02) : 255 - 267
  • [10] HIGH-RESOLUTION G-BANDED CHROMOSOMES OF THE MOUSE
    SAWYER, JR
    MOORE, MM
    HOZIER, JC
    [J]. CHROMOSOMA, 1987, 95 (05) : 350 - 358