Association of Multiple Sclerosis and Celiac Disease: Case Report

被引：0

作者：

Uludag, Irem Fatma ^{[1
]}

Kulu, Ugur ^{[1
]}

Sener, Ufuk ^{[1
]}

Zorlu, Yasar ^{[1
]}

Erdogan, Isin Gokcol ^{[2
]}

机构：

[1] Izmir Tepecik Training & Res Hosp, Dept Neurol, Izmir, Turkey

[2] Izmir Tepecik Training & Res Hosp, Dept Biochem, Izmir, Turkey

来源：

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI | 2011年 / 31卷 / 01期

关键词：

Celiac disease; multiple sclerosis; demyelinating autoimmune diseases; CNS; autoimmune diseases; GLUTEN SENSITIVITY; T-CELLS; MORPHOLOGY;

D O I：

10.5336/medsci.2009-12658

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The association of multiple sclerosis and celiac disease is recently described in case reports although clinical significance of this association is not clear, and it is difficult to decide whether observed neurologic abnormalities originate due to celiac disease itself or suspected accompanying multiple sclerosis. The association of multiple sclerosis and celiac disease, if present may be due to a common genetic or autoimmune basis. Our case is a 16-year-old male who developed celiac disease 2.5 years after the diagnosis of multiple sclerosis. Duodenal biopsy was positive and the patient responded well to the gluten-free diet.

引用

页码：240 / 244

页数：5

共 15 条

[1]

BATESON MC, 1979, LANCET, V1, P1108

[2] Coeliac disease [J].

Di Sabatino, Antonio ;

Corazza, Gino Roberto .

LANCET, 2009, 373 (9673) :1480-1493

[3] Case of multiple sclerosis with atypical onset associated with autoimmune hepatitis and silent coeliac disease [J].

Ferro, Maria Teresa ;

Franciotta, Diego ;

Riccardi, Tommaso ;

D'Adda, Elisabetta ;

Mainardi, Elsa ;

Montanelli, Alessandro .

NEUROLOGICAL SCIENCES, 2008, 29 (01) :29-31

[4] Neurological disorders in adult celiac disease [J].

Freeman, Hugh J. .

CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2008, 22 (11) :909-911

[5] Regulatory T cells fail to suppress CD4+ T-bet+ T cells in relapsing multiple sclerosis patients [J].

Frisullo, Giovanni ;

Nociti, Viviana ;

Iorio, Raffaele ;

Patanella, Agata K. ;

Caggiula, Marcella ;

Marti, Alessandro ;

Sancricca, Cristina ;

Angelucci, Francesco ;

Mirabella, Massimiliano ;

Tonali, Pietro A. ;

Batocchi, Anna P. .

IMMUNOLOGY, 2009, 127 (03) :418-428

[6] Increased CD4+CD25+Foxp3+ T cells in peripheral blood of celiac disease patients: Correlation with dietary treatment [J].

Frisullo, Giovanni ;

Nociti, Viviana ;

Iorio, Raffaele ;

Patanella, Agata Katia ;

Marti, Alessandro ;

Assunta, Bianco ;

Plantone, Domenico ;

Cammarota, Giovanni ;

Tonali, Pietro Attilio ;

Batocchi, Anna Paola .

HUMAN IMMUNOLOGY, 2009, 70 (06) :430-435

[7] Headache and CNS white matter abnormalities associated with gluten sensitivity [J].

Hadjivassiliou, M ;

Grünewald, RA ;

Lawden, M ;

Davies-Jones, GAB ;

Powell, T ;

Smith, CML .

NEUROLOGY, 2001, 56 (03) :385-388

[8]

Idiman E, 2009, TURKIYE KLINIKLERI J, V2, P30

[9] Gluten sensitivity and neuromyelitis optica: two case reports [J].

Jacob, S ;

Zarei, M ;

Kenton, A ;

Allroggen, H .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2005, 76 (07) :1028-1030

[10] New developments in celiac disease [J].

Jennings, JSR ;

Howdle, PD .

CURRENT OPINION IN GASTROENTEROLOGY, 2003, 19 (02) :118-129

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