In vitro activities of four novel triazoles against Scedosporium spp.

被引：137
作者：
Carrillo, AJ
Guarro, J
机构：
[1] Univ Rovira & Virgili, Fac Med, Unitat Microbiol, E-43201 Reus, Spain
[2] Univ Rovira & Virgili, Inst Estudis Avancats, E-43201 Reus, Spain
[3] Asesoria Cient & Invest Aplicada, Dept Microbiol, Barcelona 08037, Spain
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 07期
关键词：
D O I：
10.1128/AAC.45.7.2151-2153.2001
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
In order to develop new approaches to the treatment of the severe and usually fatal infections caused by Scedosporium spp., the in vitro antifungal activities of four novel triazoles (posaconazole, ravuconazole, voriconazole, and UR-9825) and some current antifungals (amphotericin B, ketoconazole, itraconazole, and nystatin) were determined. The latter group was clearly ineffective against the two species tested. The four new antifungals showed activity against Scedosporium apiospermum, and UR-9825 and voriconazole were active against S. prolificans.
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页码：2151 / 2153
页数：3
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