Modular synthesis of allosteric inhibitors of p97 AAA ATPase

被引：0
|
作者：
Carder, Evan [1 ]
Huryn, Donna [1 ]
Wipf, Peter [1 ]
机构：
[1] Univ Pittsburgh, Pittsburgh, PA USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2018年 / 256卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
214
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Development of p97 AAA ATPase inhibitors
    Chou, Tsui-Fen
    Deshaies, Raymond J.
    AUTOPHAGY, 2011, 7 (09) : 1091 - 1092
  • [2] Design and synthesis of heterocyclic inhibitors of the AAA ATPase p97
    LaPorte, Matthew
    Houghton, Michael
    Colombo, Raffaele
    Yue, Zhizhou
    Alverez, Celeste
    Kovaliov, Marina
    Lim, Chaemin
    Samankumura, Lalith
    Yan, Yongzhao
    Green, Neal
    Moore, William
    Mroczkowski, Barbara
    Bulfer, Stacie
    Neitz, Jeffrey
    Arkin, Michelle
    Huryn, Donna
    Wipf, Peter
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [3] Discovery, optimization and characterization of allosteric inhibitors of the AAA ATPase p97, an emerging cancer target
    Huryn, Donna
    Arkin, Michelle
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
  • [4] Structure of the AAA ATPase p97
    Zhang, XD
    Shaw, A
    Bates, PA
    Newman, RH
    Gowen, B
    Orlova, E
    Gorman, MA
    Kondo, H
    Dokurno, P
    Lally, J
    Leonard, G
    Meyer, H
    van Heel, M
    Freemont, PS
    MOLECULAR CELL, 2000, 6 (06) : 1473 - 1484
  • [5] Side chain optimizations of novel inhibitors of the AAA ATPase p97
    Alverez, Celeste
    Kovaliov, Marina
    Laporte, Matthew
    Lim, Chaemin
    Colombo, Raffaele
    Yue, Zhizhou
    Bulfer, Stacie
    Arkin, Michelle
    Huryn, Donna
    Wipf, Peter
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [6] Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97
    LaPorte, Matthew G.
    Burnett, James C.
    Colombo, Raffaele
    Bulfer, Stacie L.
    Alverez, Celeste
    Chou, Tsui-Fen
    Neitz, R. Jeffrey
    Green, Neal
    Moore, William J.
    Yue, Zhizhou
    Li, Shan
    Arkin, Michelle R.
    Wipf, Peter
    Huryn, Donna M.
    ACS MEDICINAL CHEMISTRY LETTERS, 2018, 9 (11): : 1075 - 1081
  • [7] 2-Phenyl indole piperazine inhibitors of AAA ATPase p97
    Chatterley, Alexander
    Miller, Eric
    Alverez, Celeste
    Kovaliov, Marina
    Lim, Chaemin
    Colombo, Raffaele
    Yue, Zhizhou
    LaPorte, Matt
    Samankumura, Lalith
    Bulfer, Stacie
    Arkin, Michelle
    Huryn, Donna
    Wipf, Peter
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [8] Inhibitors of the AAA+ Chaperone p97
    Chapman, Eli
    Maksim, Nick
    de la Cruz, Fabian
    La Clair, James J.
    MOLECULES, 2015, 20 (02): : 3027 - 3049
  • [9] Hierarchical Binding of Cofactors to the AAA ATPase p97
    Haenzelmann, Petra
    Buchberger, Alexander
    Schindelin, Hermann
    STRUCTURE, 2011, 19 (06) : 833 - 843
  • [10] The AAA+ ATPase p97, a cellular multitool
    Stach, Lasse
    Freemont, Paul S.
    BIOCHEMICAL JOURNAL, 2017, 474 : 2953 - 2976
12345