Effect of heat treatment of starch on the properties of the starch hydrogels

被引:51
作者
Pal, Kunal [2 ]
Banthia, A. K. [1 ]
Majumdar, D. K. [3 ]
机构
[1] Indian Inst Technol, Ctr Mat Sci, Kharagpur 721302, W Bengal, India
[2] Ryerson Univ, Sch Nutr, Toronto, ON M5B 2K3, Canada
[3] Univ Delhi, Coll Pharm, Delhi Inst Pharmaceut Sci & Res, New Delhi 110017, India
关键词
hydrogels; corn starch; polyvinyl alcohol; Crosslinking;
D O I
10.1016/j.matlet.2007.04.113
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Development of hydrogels prepared by crosslinking of corn starch and polyvinyl alcohol with glutaraldehyde was attempted. The membranes were characterized by FTIR spectroscopy and XRD. The mechanical properties of the hydrogels were characterized by tensile tests. Diffusion studies of salicylic acid and gatifloxacin through the membranes were also evaluated. FTIR spectroscopy indicated absence of carbonyl group absorption band of glutaraldehyde and presence of hydroxyl group in the hydrogel membranes. XRD studies indicated that the crystallinity of the membranes was mainly due to PVA. The membranes had sufficient strength to be used for biomedical applications. Diffusion studies indicated diffusion of both anionic and cationic drugs through the hydrogel membranes. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:215 / 218
页数:4
相关论文
共 9 条
[1]  
BHAT SV, 2002, BIOMATERIALS, P106
[2]   Bioartificial polymeric materials based on polysaccharides [J].
Cascone, MG ;
Barbani, N ;
Cristallini, C ;
Giusti, P ;
Ciardelli, G ;
Lazzeri, L .
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2001, 12 (03) :267-281
[3]   Polysaccharide hydrogels for protein drug delivery [J].
Chen, J ;
Jo, S ;
Park, K .
CARBOHYDRATE POLYMERS, 1995, 28 (01) :69-76
[4]  
HASHIM K, 2000, INT S RAD TECHN EM I, P79
[5]   Radiation modification of water absorption of cassava starch by acrylic acid/acrylamide [J].
Kiatkamjornwong, S ;
Chomsaksakul, W ;
Sonsuk, M .
RADIATION PHYSICS AND CHEMISTRY, 2000, 59 (04) :413-427
[6]  
Pal K, 2006, J Appl Biomater Biomech, V4, P38
[7]  
PAL K, 2006, J BIOMATERIALS APPL
[8]   Preparation and characterization of polyvinyl alcohol-gelatin hydrogel membranes for biomedical applications [J].
Pal, Kunal ;
Banthia, Ajit K. ;
Majumdar, Dipak K. .
AAPS PHARMSCITECH, 2007, 8 (01)
[9]   New starch-based thermoplastic hydrogels for use as bone cements or drug-delivery carriers [J].
Pereira, CS ;
Cunha, AM ;
Reis, RL ;
Vázquez, B ;
San Román, J .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 1998, 9 (12) :825-833