Hematopoietic Stem Cells and Their Roles in Tissue Regeneration

被引：73

作者：

Lee, Ji Yoon ^{[1
]}

Hong, Seok-Ho ^{[2
]}

机构：

[1] CHA Univ, CHA Adv Res Inst, Seongnam, South Korea

[2] Kangwon Natl Univ, Sch Med, Dept Internal Med, 1 Gangwondaehak Gil, Chunchon 24341, South Korea

来源：

INTERNATIONAL JOURNAL OF STEM CELLS | 2020年 / 13卷 / 01期

基金：

新加坡国家研究基金会;

关键词：

Hematopoietic stem cells; Stem cell therapy; Hematologic disorder; Liver disease; BONE-MARROW MONONUCLEAR; ENDOTHELIAL PROGENITOR CELLS; AGE-RELATED-CHANGES; LIVER-CIRRHOSIS; CD34(+) CELLS; STEM/PROGENITOR CELLS; AUTOLOGOUS INFUSION; HEPATIC-ARTERY; CD133(+) CELLS; TRANSPLANTATION;

D O I：

10.15283/ijsc19127

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Hematopoietic stem cells (HSCs) are regarded as one of essential cell sources for treating regenerative diseases. Among many stem cells, the feasibility of using adult-derived hematopoietic stem cells in therapeutic approaches is very diverse, and is unarguably regarded as an important cell source in stem cell biology. So far, many investigators are exploring HSCs and modified HSCs for use in clinical and basic science. In the present review, we briefly summarized HSCs and their application in pathophysiologic conditions, including non-hematopoietic tissue regeneration as well as blood disorders. HSCs and HSCs-derived progenitors are promising cell sources in regenerative medicine and their contributions can be properly applied to treat pathophysiologic conditions. Among many adult stem cells, HSCs are a powerful tool to treat patients with diseases such as hematologic malignancies and liver disease. Since HSCs can be differentiated into diverse progenitors including endothelial progenitors, they may be useful for constructing strategies for effective therapy.

引用

页码：1 / 12

页数：12

共 84 条

[21] Granulocyte Colony-Stimulating Factor Mobilizes CD34+ Cells and Improves Survival of Patients With Acute-on-Chronic Liver Failure [J].

Garg, Vishal ;

Garg, Hitendra ;

Khan, Arshi ;

Trehanpati, Nirupama ;

Kumar, Ashish ;

Sharma, Barjesh Chander ;

Sakhuja, Puja ;

Sarin, Shiv Kumar .

GASTROENTEROLOGY, 2012, 142 (03) :505-U156

[22] Characterization and clinical application of human CD34+ stem/progenitor cell populations mobilized into the blood by granulocyte colony-stimulating factor [J].

Gordon, Myrtle Y. ;

Levicar, Natasa ;

Pai, Madhava ;

Bachellier, Philippe ;

Dimarakis, Ioannis ;

Al-Allaf, Faisal ;

M'Hamdi, Hanane ;

Thalji, Tamara ;

Welsh, Jonathan P. ;

Marley, Stephen B. ;

Davies, John ;

Dazzi, Francesco ;

Marelli-Berg, Federica ;

Tait, Paul ;

Playford, Raymond ;

Jiao, Long ;

Jensen, Steen ;

Nicholls, Joanna P. ;

Ayav, Ahmet ;

Nohandani, Mahrokh ;

Farzaneh, Farzin ;

Gaken, Joop ;

Dodge, Rikke ;

Alison, Malcolm ;

Apperley, Jane F. ;

Lechler, Robert ;

Habib, Nagy A. .

STEM CELLS, 2006, 24 (07) :1822-1830

[23] Controlled trials in hepatitis B virus-related decompensate liver cirrhosis: peripheral blood monocyte transplant versus granulocyte-colony-stimulating factor mobilization therapy [J].

Han, Y. ;

Yan, L. ;

Han, G. ;

Zhou, X. ;

Hong, L. ;

Yin, Z. ;

Zhang, X. ;

Wang, S. ;

Wang, J. ;

Sun, A. ;

Liu, Z. ;

Xie, H. ;

Wu, K. ;

Ding, J. ;

Fan, D. .

CYTOTHERAPY, 2008, 10 (04) :390-396

[24] Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells [J].

Jackson, KA ;

Majka, SM ;

Wang, HG ;

Pocius, J ;

Hartley, CJ ;

Majesky, MW ;

Entman, ML ;

Michael, LH ;

Hirschi, KK ;

Goodell, MA .

JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (11) :1395-1402

[25] Hepatic stem/progenitor cells and stem-cell transplantation for the treatment of liver disease [J].

Kakinuma, Sei ;

Nakauchi, Hiromitsu ;

Watanabe, Mamoru .

JOURNAL OF GASTROENTEROLOGY, 2009, 44 (03) :167-172

[26] Controversies and Recent Advances in Hematopoietic Cell Transplantation for Follicular Non-Hodgkin Lymphoma [J].

Kanate, Abraham S. ;

Kharfan-Dabaja, Mohamed A. ;

Hamadani, Mehdi .

BONE MARROW RESEARCH, 2012,

[27] Safety and efficacy of autologous bone marrow stem cell transplantation through hepatic artery for the treatment of chronic liver failure: A preliminary study [J].

Khan, A. A. ;

Parveen, N. ;

Mahaboob, V. S. ;

Rajendraprasad, A. ;

Ravindraprakash, H. R. ;

Venkateswarlu, J. ;

Rao, S. G. A. ;

Narusu, M. Lakshmi ;

Khaja, M. N. ;

Pramila, R. ;

Habeeb, A. ;

Habibullah, C. M. .

TRANSPLANTATION PROCEEDINGS, 2008, 40 (04) :1140-1144

[28]

Khan AA, 2010, CELL TRANSPLANT, V19, P409, DOI 10.3727/096368910X498241

[29] Autologous Bone Marrow Infusion Activates the Progenitor Cell Compartment in Patients With Advanced Liver Cirrhosis [J].

Kim, Ja Kyung ;

Park, Young Nyun ;

Kim, Jin Seok ;

Park, Mi-Suk ;

Paik, Yong Han ;

Seok, Jae-Yeon ;

Chung, Yong Eun ;

Kim, Hyun Ok ;

Kim, Kyung Sik ;

Ahn, Sang Hoon ;

Kim, Do Young ;

Kim, Myeong-Jin ;

Lee, Kwan Sik ;

Chon, Chae Yoon ;

Kim, Soo Jeong ;

Terai, Shuji ;

Sakaida, Isao ;

Han, Kwang-Hyub .

CELL TRANSPLANTATION, 2010, 19 (10) :1237-1246

[30] Perivascular Cells and NADPH Oxidase Inhibition Partially Restore Hyperglycemia-Induced Alterations in Hematopoietic Stem Cell and Myeloid-Derived Suppressor Cell Populations in the Bone Marrow [J].

Kim, Ji-Young ;

Lee, Ji Yoon ;

Ha, Kwon-Soo ;

Han, Eun-Taek ;

Park, Woo Sun ;

Min, Chang-Ki ;

Hong, Seok-Ho .

INTERNATIONAL JOURNAL OF STEM CELLS, 2019, 12 (01) :63-72

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