Fecal microbiota transplantation for recurrent Clostridium difficile infection in children

被引:13
作者
Chen, Becky [1 ]
Avinashi, Vishal [1 ]
Dobson, Simon [2 ]
机构
[1] British Columbia Childrens Hosp, Div Gastroenterol Hepatol & Nutr, Vancouver, BC, Canada
[2] British Columbia Childrens Hosp, Div Infect Dis, Vancouver, BC, Canada
关键词
Clostridium difficile; Fecal microbiota transplantation; Microbiome; INFLAMMATORY-BOWEL-DISEASE; RISK-FACTORS; HOSPITALIZED CHILDREN; HYPERVIRULENT STRAIN; PEDIATRIC-PATIENTS; UNITED-STATES; DIARRHEA; EPIDEMIOLOGY; MORTALITY; INFANTS;
D O I
10.1016/S0163-4453(17)30202-5
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Fecal microbiota transplantation (FMT) is a relatively simple, promising treatment for recurrent Clostridium difficile infection. While there are a wide variety of approaches including mode of delivery, the results are nonetheless encouraging, even amongst younger children. Experience with FMT in the pediatric population is increasing, showing similar success compared to adults. This article will provide an overview of C. difficile infection along with review of the rationale, methods and complications of FMT including the current experience of FMT in children. (C) 2017 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:S120 / S127
页数:8
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