A novel fluorescent probe for formaldehyde based-on monomer-excimer conversion and its imaging in live cells

被引：18
|
作者：
Han, Baichuan [1 ]
Sun, Jin [1 ]
Chen, Kai [1 ]
Chen, Zhiyong [2 ]
Huang, Minhua [2 ]
Gao, Zhenzhong [1 ]
Hou, Xianfeng [1 ]
机构：
[1] South China Agr Univ, Coll Mat & Energy, Guangzhou 510642, Guangdong, Peoples R China
[2] Natl Analyt Ctr China, Zhongshan Collaborat Innovat Ctr, Zhongshan 528476, Peoples R China
来源：
TETRAHEDRON | 2018年 / 74卷 / 50期
关键词：
Fluorescent probe; Formaldehyde; Monomer-excimer conversion; Bio-imaging; AGGREGATION-INDUCED EMISSION; SELECTIVE DETECTION; ENDOGENOUS FORMALDEHYDE; ANTHRACENE; CHEMOSENSOR; ENSEMBLE; SULFIDE; ACID; HG2+; RED;
D O I：
10.1016/j.tet.2018.10.051
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel fluorescent probe was developed for formaldehyde, which can be synthesized by one-step Buchwald-Hartwig reaction. When hydrazino-group of probe reacted with formaldehyde, hydrophobic reaction product aggregates into nanoparticles and results in the blue fluorescence due to the monomer-excimer effect. With enough sensitivity, high selectivity, good stability in physiological pH range and excellent biocompatibility, this probe can image formaldehyde in living cells. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码：7193 / 7197
页数：5
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